The effects of burimamide and metiamide on gastric secretion in the conscious cat |
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| Authors: | D. Harris J. R. Smy J. D. Reed C. W. Venables |
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| Affiliation: | 1. School of Pharmacy, Sunderland Polytechnic, Sunderland, England
2. Departments of Physiology and Surgery, University of Newcastle upon Tyne, England
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| Abstract: | Burimamide has been shown to have an acid stimulating action in the conscious cat when injected during basal conditions. Metiamide does not stimulate gastric acid secretion and when injected in addition to burimamide reduces the acid secretion seen to that drug. These results suggest a possible partial agonist action of burimamide, an action not shared by metiamide. |
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