Study of platelet indices in pregnancy-induced hypertension |
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| Affiliation: | 1. Assitant Professor, Army College of Medical Sciences, New Delhi, India;2. Professor & Head, Department of Pathology, Armed Forces Medical College, Pune, 411040, India;1. Joint Director & Officer in Charge, Centre for Arboviral and Zoonotic Diseases, National Centre for Diseases Control, 22, Shamnath Marg, Civil Line, New Delhi, India;2. Deputy Director, Centre for Arboviral and Zoonotic Diseases, National Centre for Diseases Control, 22, Shamnath Marg, Civil Line, New Delhi, India;3. Assistant Director, Centre for Arboviral and Zoonotic Diseases, National Centre for Diseases Control, 22, Shamnath Marg, Civil Line, New Delhi, India;4. Director, National Centre for Diseases Control, 22, Shamnath Marg, Civil Line, New Delhi, India;1. Tatvan State Hospital, Department of Obstetrics and Gynecology Clinic, Bitlis, Turkey;2. Aksehir State Hospital, Department of Obstetrics and Gynecology Clinic, Konya, Turkey;3. Department of Obstetrics and Gynecology, Kahramanmaras Sutcu Imam University, School of Medicine, Kahramanmaraş, Turkey;1. Department of General Surgery, Prince Hashem Bin Abdullah II, Jordan;2. Department of Anesthesia and Intensive Care, King Husain Medical Center, Jordan;1. Classified Specialist (Pharmacology), Base Hospital, Delhi Cantt, India;2. Commandant, 174 Military Hospital, C/o 56 APO, India;3. DADH, HQ 7 Inf Div, C/o 56 APO, India;4. Medical Cadet, Army College of Medical Sciences, Delhi Cantt, India;5. Associate Professor (Pharmacology), Army College of Medical Sciences, Delhi Cantt, India;1. Associate Professor and Head (Radiation Oncology Centre), Command Hospital (Air Force), Bangalore 560007, India;2. Medical Physicist (Radiation Oncology Centre), INHS Asvini, Colaba, Mumbai 400005, India;3. Senior Advisor (Radiology), INHS Asvini, Colaba, Mumbai 400005, India |
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| Abstract: | BackgroundHypertension encountered during pregnancy could be the first sign of a preexisting pathology that can significantly attribute to unfavorable maternal, fetal, and neonatal outcomes. Resolving hypertensive disorders at an early age may not alter the course and proficiency of the disease, but timely detection and treatment can not only prevent hypertensive crisis but also alter unfavorable fetal outcomes. Ipso facto, an early cataloging plays an essential role in predicting the outcome of pregnancy, both for mother and baby. Platelet indices correlate with functional status of platelets and are an emerging risk marker for detecting an impending adverse outcome in pregnancy-induced hypertension (PIH). The aim of this study was to analyze the consociation between platelet indices and severity of PIH.MethodsA prospective hospital-based study was undertaken on 100 cases diagnosed with PIH (preeclampsia [PE; 88 cases] and eclampsia [12 cases and 100 controls]).ResultsMost cases occurred in the age group of 22–26 years (43.3%) and in primigravidae (55.8%). Analysis of platelet volume indices (PVI) indicated mean platelet volume (MPV), platelet distribution width (PDW), and platelet–large cell ratio (P-LCR) as significant risk factors for developing hypertensive crisis. This was in concordance with the elevated blood pressures.ConclusionThe study concludes that platelet indices are raised in patients who have PIH as compared with normal pregnancies. |
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| Keywords: | Pregnancy Induced Hypertension Maternal mortality Pre-eclampsia Eclampsia Platelets |
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