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Ultrasound-guided thrombin injection versus ultrasound-guided compression therapy of iatrogenic femoral false aneurysms: Single center experience
Institution:1. Vascular Surgery, King Hussin Medical Center, Amman, Jordan;2. Radiology, King Hussin Medical Center, Amman, Jordan;1. Resident, Department of Ophthalmology, Armed Forces Medical College, Pune 411040, India;2. Associate Professor, Department of Ophthalmology, Armed Forces Medical College, Pune 411040, India;3. Consultant (Ophthalmology), Command Hospital (Eastern Command), Kolkata 700027, India;4. Assistant Professor (Ophthalmology), Command Hospital (Southern Command), Pune 411040, India;1. Associate Professor (Microbiology), SHKM Government Medical College, Mewat, Haryana, India;2. Professor & Head, Department of Microbiology, Armed Forces Medical College, Pune 411040, India;3. Dean, Armed Forces Medical College, Pune 411040, India;4. Professor of Medicine & Rheumatology, Department of General Hospital, Sree Balaji Medical College & Hospital, Chennai, India;5. Director General Medical Services (Air), O/o DGMS (Air), IHQ, Air Headquarter, RK Puram, New Delhi 110066, India;1. Cdr (MS) Health O/o DGMS (Navy), IHQ MoD (Navy), Sena Bhawan, New Delhi 110011, India;2. C503, Sector A, Jal Vayu Vihar, Powai, Mumbai 400076, India;3. Classified Specialist (Aerospace Medicine), Oi/c Hyperbaric Medicine, Dept of HAP&HM, IAM IAF, Bengaluru 560017, India;1. Classified Specialist (Marine Medicine), Integrated Headquarters of MOD (Navy), Sena Bhawan, New Delhi, India;2. Graded Specialist (Surgery), INHS Kalyani, Vishakhapatnam, Andhra Pradesh, India;3. Graded Specialist (Anaesthesiology), INHS Jeevanti, Goa, India;4. Classified Specialist (Marine Medicine) & PMO, INS Satavahana, Vishakhapatnam, Andhra Pradesh, India;1. Assistant Professor, Department of Dermatology & Ven, Armed Forces Medical College, Pune 411040, India;2. Resident, Department of Dermatology & Ven, Armed Forces Medical College, Pune 411040, India;3. Senior Advisor (Dermatology), Base Hospital Lucknow, India;4. Professor & Head (Dermatology), Command Hospital (Southern Command), Pune 411040, India;1. Graded Specialist (Pulmonary Medicine) INHS Asvini, Colaba, Mumbai 400005, India;2. Senior Advisor (Marine Medicine), INHS Asvini, Colaba, Mumbai 400005, India;3. Senior Advisor and Head of Department (Medicine and Gastroenterology), INHS Asvini, Colaba, Mumbai 400005, India
Abstract:BackgroundIatrogenic femoral pseudoaneurysm (false aneurysm) due to arterial access following cardiovascular procedures is becoming common because of the increase in number and complexity of the procedures. Recently, percutaneous thrombin injection is becoming a popular treatment of these false aneurysms.The aim of this study was to assess the efficacy and safety of femoral pseudoaneurysm closure using ultrasound-guided thrombin injection in comparison to ultrasound-guided compression.MethodsA retrospective analysis was undertaken of 65 patients who presented to our vascular department with iatrogenic femoral pseudoaneurysm between January 2015 and March 2019. Twenty-five patients underwent ultrasound-guided thrombin injection, and 40 were treated using ultrasound-guided compression therapy. The primary outcome measured was efficacy, while other outcomes examined were safety, procedure duration, and cost.ResultsA total of 65 patients (45 males, 20 female) were identified with a mean age of 62 years. Out of the 65, 40 patients (28 males, 12 female) underwent ultrasound-guided compression therapy (group A) with a mean aneurysm size of 2.9 cm, and 25 (17 male, 8 female) underwent ultrasound-guided thrombin injection (group B) with a mean pseudoaneurysm sac size of 3.7 cm. The success rate of thrombosis in group A was 70% and in group B was 92%. No significant complications were reported in both groups.ConclusionsUltrasound-guided thrombin injection should be considered as the first line of treatment for uncomplicated femoral pseudoaneurysms because it has a higher thrombosis and lower recurrence rates, when compared with ultrasound-guided compression treatment.
Keywords:False aneurysm  Pseudoaneurysm  Iatrogenic compression  Ultrasound-guided thrombin
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