The inflammatory reaction to crystals |
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| Authors: | R A Terkeltaub M H Ginsberg |
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| Affiliation: | Rheumatology Section, San Diego Veterans Administration Medical Center, California. |
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| Abstract: | Acute gout serves as a relatively well-defined paradigm for the review of the pathogenesis of acute microcrystal-induced inflammation. Inflammatory mediator systems activated directly or indirectly by urate crystals, the temporal events in a gouty paroxysm, and the possible factors responsible for the wide clinical variability of acute gout and other forms of crystal-induced inflammation are discussed. |
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