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低分子肝素在预防大隐静脉曲张术后患肢深静脉血栓形成中的作用
引用本文:董春锋,王苏杭. 低分子肝素在预防大隐静脉曲张术后患肢深静脉血栓形成中的作用[J]. 医学综述, 2012, 18(16): 2673-2674
作者姓名:董春锋  王苏杭
作者单位:1. 北京市顺义区医院血管外科,北京,101300
2. 北京市顺义区医院肾内科,北京,101300
摘    要:目的探讨低分子肝素在预防大隐静脉曲张术后患肢深静脉血栓形成中的作用。方法分析200例大隐静脉曲张术后应用低分子肝素抗凝患者(观察组)及200例术后未应用低分子肝素抗凝患者(对照组)下肢深静脉血栓形成发生情况及术后患肢皮下血肿的发生情况。结果两组患者术后患肢深静脉血栓形成的发生率比较差异有统计学意义(P<0.05),术后患肢皮下血肿发生率比较差异无统计学意义(P>0.05)。结论大隐静脉曲张术后应用低分子肝素抗凝治疗,可显著降低下肢深静脉血栓形成的发生,同时不增加患肢术后出血的风险。

关 键 词:大隐静脉曲张  下肢深静脉血栓形成  低分子肝素  抗凝治疗

The Efficacy of Low Molecular Weight Heparin in Prevention Deep of Vein Thrombosis after the Operation of Great Saphenous Varicose Vein
DONG Chun-feng , WANG Su-hang. The Efficacy of Low Molecular Weight Heparin in Prevention Deep of Vein Thrombosis after the Operation of Great Saphenous Varicose Vein[J]. Medical Recapitulate, 2012, 18(16): 2673-2674
Authors:DONG Chun-feng    WANG Su-hang
Affiliation:1.Department of Vascular Surgery;2.Department of Nephrology,Beijing Shunyi Hospital,Beijing 101300,China)
Abstract:Objective To investigate the efficacy of low molecular weight heparin in prevention deep vein thrombosis(DVT)after the operation of great saphenous varicose vein.Methods The DVT incidence of 200 case of great saphenous varicose vein who were given low molecular weight heparin after operation(observation group)and 200 case of great saphenous varicose vein who were not given low molecular weight heparin after operation(control group)were analyzed,and the incidence of subcutaneous hematoma of the two groups were observed.Results There was significant difference between the two groups in DVT incidence(P<0.05),and there was no difference between the two groups in subcutaneous hematoma incidence(P>0.05).Conclusion The therapy of the low molecular weight heparin after the operation of great saphenous varicose vein can reduce the incidence of DVT,without increasing the incidence of subcutaneous hematoma.
Keywords:Great saphenous varicose vein  Lower limb deep vein thrombosis  Low molecular weight heparin  Anticoagulant therapy
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