中山地区54258例育龄人群G6PD筛查结果分析

目的通过大样本的筛查了解中山地区育龄人群G6PD的分布情况。方法以紫外速率法检测54258例育龄人群的静脉血液红细胞中葡萄糖-6-磷酸脱氢酶的活性，将G6PD活性按缺乏、正常和增高进行分组。结果中山地区G6PD酶活性检出率分别为：缺乏组4．33％、正常组94．75％、增高组0．92％，其中缺乏组检出率男性高于女性，增高组检出率男性低于女性。结论中山地区是G6PD缺乏症的高发地区，对育龄人群进行G6PD筛查，并进行优生优育的合理指导，是减少出生缺陷和提高出生人口质量的必要措施。

Analysis on G6PD examination among 54 258 persons at reproduction-age in Zhongshan City.

To find out the glucose-6-phosphate dehyfrogenase incidence in Zhongshan area among the large sample. Methods： Blood samples from 54 258 persons at reproduction-age were examined on G6PD activity with UV rate method, and then grouping the G6PD activity according to the deficiency, normality and the higer. Results： There were 2350 patients whose ratio of incidence of G6PD deficiency is 4.33%, while the incidence of G6PD normality is 94.75% and the higer group is 0.92%.The incidence of male is higer than the female in the G6PD deficienty, but lower in the higer group. Conclusion： There is a high incidence of G6PD deficiency in Zhongshan City. It is necessary to examine blood samples on G6PD among persons at reproduction-age for healthy child rearing, reducing birth defects and the improvement of the population quality.