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低出生体重儿的发生与母亲既往生育史的相关性分析
引用本文:王卫凯,;杨兰,;仇杰,;蔺茹,;徐瑞峰.低出生体重儿的发生与母亲既往生育史的相关性分析[J].中国优生与遗传杂志,2014(11):114-117.
作者姓名:王卫凯  ;杨兰  ;仇杰  ;蔺茹  ;徐瑞峰
作者单位:[1]兰州大学公共卫生学院,甘肃兰州730000; [2]甘肃省妇幼保健院,甘肃兰州730050
摘    要:目的探讨母亲既往生育史对单胎活产低出生体重儿发生的影响因素。方法选取375名住院产妇所生的单胎活产低出生体重儿(LBW),与同期分娩的单胎活产正常体重儿5157例进行病例对照分析,比较母亲既往生育史对低出生体重儿发生的影响。结果既往自然流产史、早产史和不良孕产史是LBW发生的危险因素(OR=1.57 95%CI1.110-2.25)、(OR=4.84 95%CI 2.01-11.66)、(OR=2.09 95%CI 1.22-3.57),并且主要针对于早产LBW(OR=1.6595%CI 1.11-2.44)、(OR=6.55 95%CI 2.70-15.91)、(OR=2.18 95%CI 1.21-3.91),既往低出生体重史是足月LBW发生的危险因素(OR=7.93 95%CI 1.72-36.46)结论 LBW的发生与既往自然流产史、早产史、不良孕产史、低出生体重史密切相关。对以上这些妇女再次怀孕的孕前、孕期均应做好保健服务,以有效减少LBW的发生。

关 键 词:单胎活产  低出生体重  既往生育史  病例对照研究  非条件Logistic回归

Correlation analysis between the pregnancy previous reproductive history and low birth weight infant
Institution:WANG Wei-kai,YAN Lan,QIU Jie,LIN Ru,XU Rui-feng (1.The School of Public Health of Lanzhou University, Lanzhou 730000; 2.Gansu Provincial Maternity and Child-care Hospital, Lanzhou 730050, Gansu, China)
Abstract:Objective:Discussion of the occurred factors between the pregnancy previous reproductive history and single live low birth weight infant. Methods:Select 375 hospitalized single live low birth weight infants(LBW). With the same period single live normal birth weight infants performed a case-control analysis of 5157 cases. Comparative effects of the prenancy previous reproductive history of low birth weight infant occurred. Results:Past history of spontaneous abortion,preterm birth and adverse pregnancy history are the risk factors(OR=1.57 95% CI 1.110-2.25)LBW occurred(OR=4.84 95% CI 2.01-11.66),(OR=2.09 95% CI 1.22-3.57),and is primarily targeted at preterm LBW(OR=1.65 95% CI 1.11-2.44),(OR=6.5595% CI 2.70-15.91),(OR=2.18 95% CI 1.21-3.91),previous low birth weight history is a risk factor(OR=7.93 95% CI 1.72-36.46)term LBW occurred. Conclusion:Low birth weight is closely associated with previous spontaneous abortion. Preterm birth history,adverse pregnancy history,history of low birth weight.For these women pregnant again before pregnancy,during pregnancy should make health services,in order to effectively reduce the incidence of LBW.
Keywords:Single live births  LBW  previous reproductive history  A case-control study  Non-conditional logistic regression
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