耐药结核病的管理 |
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引用本文: | Alison grant,;Philip Gothard,;GUY Thwaites,;范永德[译],;张燕[译],;赵艳平[译],;何广学[校]. 耐药结核病的管理[J]. 英国医学杂志, 2008, 0(6): 351-356 |
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作者姓名: | Alison grant, Philip Gothard, GUY Thwaites, 范永德[译], 张燕[译], 赵艳平[译], 何广学[校] |
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作者单位: | [1]Hospital for Tropical Diseases, University College London Hospitals NHS Foundation Trust, London WC1E 6JB; [2]CLinical Research Unit, London School of Hygiene & Tropical Medicine, London WCIE 7HT; [3]Centre for Molecular Microbiology and Infection, Imperial College, London SW7 2AZ; [4]不详, Imperial College, London SW7 2AZ; |
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基金项目: | 致谢:We thank the World Heath Organization for providing figure 1. AG is supported by a public health career scientist award from the UK Department of Health and GT is funded by an intermediate fellowship from the Welleome Trust. All authors receive support from the UCLH/ UCIVLSHTM Comprehensive Biomedical Research Centre. 关于作者(Contributors) : The authors wrote the article jointly and are all guarantors. |
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摘 要: | 耐药结核病越来越普遍,然而传统的实验室方法确诊耐药比较慢,而且实验室的特殊要求也使其很难普及。在资源条件好的地方,快速分子生物学方法的应用在增加。简单、便宜的替代方法在资源受限地区的应用也有了进展。耐药结核病诊疗指南的依据还不充分,还需随机病例对照研究的证据支持。在英国,执行多药耐药结核病管理服务。预防结核病耐药的重要措施,包括快速诊断病例,治疗药物敏感病例和耐药病例,以及预防结核病传染。
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关 键 词: | 耐药结核病 结核病管理 病例对照研究 分子生物学方法 实验室方法 诊疗指南 证据支持 多药耐药 |
Managing drug resistant tuberculosis |
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Affiliation: | Alison grant, Philip Gothard, GUY Thwaites(1.Hospital for Tropical Diseases, University College London Hospitals NHS Foundation Trust, London WC1E 6JB,2.CLinical Research Unit, London School of Hygiene & Tropical Medicine, London WCIE 7HT,3.Centre for Molecular Microbiology and Infection, Imperial College, London SW7 2AZ) |
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