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耐药结核病的管理
引用本文:Alison grant,;Philip Gothard,;GUY Thwaites,;范永德[译],;张燕[译],;赵艳平[译],;何广学[校]. 耐药结核病的管理[J]. 英国医学杂志, 2008, 0(6): 351-356
作者姓名:Alison grant,  Philip Gothard,  GUY Thwaites,  范永德[译],  张燕[译],  赵艳平[译],  何广学[校]
作者单位:[1]Hospital for Tropical Diseases, University College London Hospitals NHS Foundation Trust, London WC1E 6JB; [2]CLinical Research Unit, London School of Hygiene & Tropical Medicine, London WCIE 7HT; [3]Centre for Molecular Microbiology and Infection, Imperial College, London SW7 2AZ; [4]不详, Imperial College, London SW7 2AZ;
基金项目:致谢:We thank the World Heath Organization for providing figure 1. AG is supported by a public health career scientist award from the UK Department of Health and GT is funded by an intermediate fellowship from the Welleome Trust. All authors receive support from the UCLH/ UCIVLSHTM Comprehensive Biomedical Research Centre. 关于作者(Contributors) : The authors wrote the article jointly and are all guarantors.
摘    要:耐药结核病越来越普遍,然而传统的实验室方法确诊耐药比较慢,而且实验室的特殊要求也使其很难普及。在资源条件好的地方,快速分子生物学方法的应用在增加。简单、便宜的替代方法在资源受限地区的应用也有了进展。耐药结核病诊疗指南的依据还不充分,还需随机病例对照研究的证据支持。在英国,执行多药耐药结核病管理服务。预防结核病耐药的重要措施,包括快速诊断病例,治疗药物敏感病例和耐药病例,以及预防结核病传染。

关 键 词:耐药结核病  结核病管理  病例对照研究  分子生物学方法  实验室方法  诊疗指南  证据支持  多药耐药

Managing drug resistant tuberculosis
Affiliation:Alison grant, Philip Gothard, GUY Thwaites(1.Hospital for Tropical Diseases, University College London Hospitals NHS Foundation Trust, London WC1E 6JB,2.CLinical Research Unit, London School of Hygiene & Tropical Medicine, London WCIE 7HT,3.Centre for Molecular Microbiology and Infection, Imperial College, London SW7 2AZ)
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