斑点追踪超声心动图评价冠心病病人左心室收缩功能的研究

目的:应用超声二维斑点追踪技术（STI）评价冠心病病人左心室整体收缩期纵向应变（GLS）及18节段收缩期峰值纵向应变（LS）的变化。方法:选择经冠状动脉造影证实的冠状动脉狭窄≥50%的病例组35例和无冠状动脉狭窄的对照组25例，测量2组左心室GLS、左心室心尖两腔、四腔和三腔切面（AP2，AP4，AP3）的LS和18节段的LS。结果:2组GLS比较差异有统计学意义（P<0.01），病例组基底段、前间隔和下壁中间段、前壁和后间隔的心尖段与对照组比较，其LS绝对值降低（P<0.05）；左心室的AP2、AP4、AP3的LS与对照组比较差异无统计学意义（P>0.05）。结论:STI超声心动图能够定量评价冠心病病人左心室心肌收缩运动的早期变化。

Study on speckle tracking imaging echocardiography in the evaluation of systolic function of left vertricle in patients with coronary heart disease

Objective:To evaluate the changes of global longitudinal strain(GLS) and 18 segments peak systolic longitudinal strain(LS) of left vertricle in patients with coronary heart disease(CHD) using speckle tracking imaging(STI).Methods:Thirty-five CHD patients with coronary artery stenosis rate ≥ 50% diagnosed by coronary angiography(CAG) and 25 patients without coronary artery stenosis were divided into the case group and control group,respectively.The LS of the apical four chamber views,two chamber views and three chamber views(AP4,AP2,AP3),GLS and 18 segments LS of the left vertricle were calculated in two groups.Results:The difference of the GLS between two groups was statistically significant(P<0.01).The LS in base segments of all wall,middle segments of anterior septum and inferior wall,apex segments of anterior wall and posterior septum in case group were lower than those in control group(P<0.05).The differences of LS of AP2,AP4 and AP3 in left ventricle between two groups were not statistically significant(P>0.05).Conclusions:STI echocardiography can quantitatively evaluate the early changes of the left vertricle myocardial systolic movement in patients with CHD.