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Patient and physician perspectives and experiences of basal insulin titration in type 2 diabetes in the United States: Cross-sectional surveys
Authors:Stewart B. Harris MD  Kamel Mohammedi MD  Monica Bertolini MD  Maureen Carlyle MPH  Valery Walker MSc  Fang Liz Zhou MD  John E. Anderson MD  Jochen Seufert MD
Affiliation:1. Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, Canada;2. University of Bordeaux, INSERM, BMC, U1034, Pessac, France;3. Sanofi, Bridgewater, New Jersey, USA;4. Optum, Eden Prairie, Minnesota, USA;5. The Frist Clinic, Nashville, Tennessee, USA;6. Division of Endocrinology and Diabetology, Department of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany
Abstract:

Aim

Patient- and physician-associated barriers impact the effectiveness of basal insulin (BI) titration in the management of type 2 diabetes (T2D). We evaluated the experiences of patients with T2D and physicians with BI titration education.

Materials and Methods

In this observational, cross-sectional study, patients with T2D and physicians treating patients with T2D were identified by claims in the Optum Research Database and were invited to complete a survey. Eligible patients had 12 months of continuous health-plan enrolment with medical and pharmacy benefits during the baseline period, and recent initiation of BI therapy. Eligible physicians had initiated BI for ≥1 eligible patient with T2D during the past 6 months.

Results

In total, 416 patients and 386 physicians completed the survey. Ninety per cent of physicians reported treating ≥50 patients with T2D; 66% treated ≥25% of patients with BI. Whereas 74% of patients reported that BI titration was explained to them by a physician, 96% of physicians reported doing so. Furthermore, 20% of patients stated they were offered educational materials whereas 56% of physicians reported having provided materials. Physicians had higher expectations of glycaemic target achievement than were seen in the patient survey; their main concern was the patients' ability to titrate accurately (79%).

Conclusions

There is a marked difference in patients' and physicians' experiences of BI titration education. Novel tools and strategies are required to enable effective BI titration, with more educational resources at the outset, and ongoing access to tools that provide clear, simple direction for self-titration with less reliance on physicians/health care providers.
Keywords:basal insulin  glycaemic control  hypoglycaemia  observational study  type 2 diabetes
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