三种不同给药途径预防产后出血的对比分析

目的：观察米索前列醇三种不同给药途径预防产后出血的效果。方法：将单胎头位足月妊娠阴道自然分娩的产妇300例,随机分为A、B、C3组,A组采用口服给药、B组采用直肠给药、C组采用阴道给药。结果：A组的出血量相对较小,但3组相比,差异无统计学意义（P〉0.05）;C组第三产程时间相对较短,但差异也无统计学意义（P〉0.05）。结论：米索前列酵在缩短第三产程、减少产后出血方面的效果是肯定的,米索前列醇预防产后出血的临床效果与给药途径关系不大,但阴道给药易被冲出,影响吸收、造成药物浪费,因此趋向于直肠给药和口服给药,但直肠给药应避免污染,口服要注意给药时机。

The comparative analysis of three different routes of administration on prevention of postpartum hemorrhage after cesarean section

Objective：To observe the clinical effects of three different routes of administration on prevention of postpartum hemorrhage after cesarean section.Methods：300 cases with one full-term pregnancy and fetal head position natural vaginal were randomly divided into A,B,C group,A group were treated with oral administration,B group were treated with rectal administration,C group were treated with vaginal delivery.Results：A group had relatively small amount of bleeding,but the three groups showed no significant difference（P〉0.05）.The third stage time of C group was relatively short,but had no significant difference（P〉0.05）.Conclusion：Misoprostol is more effective in reduction of postartum bleeding than oxytocin,and misoprostol in preventing postpartum hemorrhage effects and routes of administration have little to do,but easily out of the impact absorption of vaginal,resulting in a waste of drugs,it tends to rectal and oral administration,but the rectum to avoid contamination,oral administration should pay attention to the timing.