戊酸雌二醇联合醋酸甲羟孕酮治疗58例流产不全的临床观察

目的戊酸雌二醇联合醋酸甲羟孕酮治疗58例流产不全的临床疗效。方法本研究于2009年1月至2011年12月采用戊酸雌二醇联合醋酸甲羟孕酮对58例流产不全者进行治疗,并与采用催产素治疗的对照组进行临床疗效对比研究。结果两组患者经过积极的治疗后,其中研究组患者中痊愈55例,占87.93%(51/58),而对照组患者中治愈29例,占50.00%(29/58);研究组的临床治愈率明显高于对照组,且差异具有统计学意义(χ2=19.49,P<0.05)。另外,研究组患者阴道出血持续时间较对照组明显缩短,且差异具有统计学意义(t=6.12,P<0.05)。两组不良反应发生率无明显差异(χ2=0.49,P>0.05)。结论戊酸雌二醇联合醋酸甲羟孕酮治疗流产不全,提高了完全流产率,缩短了患者持续出血时间,值得临床推广使用。

Clinical Observation of 58 Cases of Incomplete Abortion Estradiol Valerate Combined Treatment of Medroxyprogesterone Acetate

Objective To pentanoic acid estradiol medroxyprogesterone acetate joint clinical curative effect for the treatment of 58 cases of incomplete abortion. Method This research in from January 2009 to December 2009 with pentanoic acid estradiol medroxyprogesterone acetate joint treatment of 58 cases of incomplete abortion, and with the use of oxytocin treatment control group in clinical effect comparison research. Results Two groups of patients after active treatment, of which the team patients recover 55 cases, 87.93 % （51/58） , while the control group were cured in 29 cases, accounting for 50.00 % （29/58） ; Clinical cure rate of group was obviously higher than that of control group, and the difference is statistically significant （chi-square= 19.49, P〈0.05） . In addition, the team obviously shorten the duration of vaginal bleeding in patients with a control group, with statistically significant difference （t=6.12, P〈0.05） . No difference between the two groups of incidence of adverse reactions （chi-square=0.49, P〉0.05） . Conclusion Pentanoic acid estradiol combined therapy with medroxyprogesterone acetate abortion is not complete, improves the complete abortion rate, shorten the patients with continuous bleeding time, worthy of clinical use.