超声三维斑点追踪技术评估左室型单心室Glenn术后心功能变化

目的 应用超声三维斑点追踪技术(three-dimensional speckle tracking imaging,3DSTI)观察左室型单心室患儿Glenn手术前、后左心功能的变化.方法 对17例左室型单心室患儿于Glenn术前及术后分别进行三维超声和心脏磁共振检查,估测左心功能;术前、术后分别与年龄、性别匹配的1...

Evaluation of the function of single left ventricle by three-dimensional speckle tracking imaging after Glenn procedure

Objective To assess the systolic function of single left ventricle before and after Glenn procedure by three-dimensional speckle tracking imaging (3DSTI). Methods Before and after Glenn procedure, the systolic function of the left ventricle was assessed by 3DSTI and cardiac magnetic resonance (CMR) in 17 children with single left ventricle, and compared with 17 age- and gender-matched healthy children (control group). Results Compared with children in the control group, end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV) of children in the single left ventricle group increased significantly (P<0.01), ejection fraction (EF), global longitudinal strain (GLS), global circumferential strain (GCS), average tangential strain (TS), average longitudinal strain (LS), average circumferential strain (CS), and average radial strain (RS) were impaired (P<0.01). After the operation, GCS, CS, and RS were significantly improved (P<0.05), but EF, GLS, GCS, TS, LS, CS, and RS were still poorer than those in the control group (P<0.05). GCS was significantly correlated with EF measured by CMR (r=-0.793, P<0.001). Conclusion Single left ventricle could be accompanied by impaired ventricular systolic function, which might be partially improved by Glenn procedure, and 3DSTI is an accurate clinical tool for the assessment of ventricular systolic function.