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血浆置换在肝移植围手术期的应用
引用本文:彭志海,邢同海,裘国强,刘育健.血浆置换在肝移植围手术期的应用[J].透析与人工器官,2004,15(2):1-5.
作者姓名:彭志海  邢同海  裘国强  刘育健
作者单位:上海市第一人民医院普通外科,上海市移植中心,上海,200800
摘    要:目的:探讨人工肝支持系统在肝移植围手术期的应用效果。方法:采用人工肝支持系统治疗5例等待供肝患者,1例肝移植术后患者。5例等待供肝患者中3例成功过渡到肝移植。结果:人工肝支持后患者肝性脑病有所好转,血清胆红素明显下降。3例成功过渡到肝移植的患者中2例痊愈出院。已存活4~6个月。结论:术前使用人工肝支持系统能改善患者一般情况;原位肝移植加人工肝支持系统是治疗慢加急肝衰竭的有效方法。

关 键 词:慢加急肝衰竭  肝移植  围手术期  血浆置换  人工肝支持系统  并发症
修稿时间:2003年8月30日

Perioperative Application of Artificial Liver Support System in Orthotopic Liver Transplantation
PENG Zhi-hai,XING Tong-hai,QIU Guo-qiang,et al.Perioperative Application of Artificial Liver Support System in Orthotopic Liver Transplantation[J].Chinese Journal of Dialysis and Artificial Organs,2004,15(2):1-5.
Authors:PENG Zhi-hai  XING Tong-hai  QIU Guo-qiang  
Institution:PENG Zhi-hai,XING Tong-hai,QIU Guo-qiang,et al Department of General Surgery,First People's Hospital,Shanghai 200080
Abstract:Objective To investigate the application of artificial liver support system (ALSS) during the perioperation of orthotopic liver transplantation(OLT).Methods:We applied ALSS to treat 5 patients wating donor liver and one patient received OLT.3 patients successfully underwent OLT.Results:Improvement degree of encephalopath and reduction in serum bilirubin were achieved in all cases after ALSS.2 patients have had excellent quality of life for 4 to 6 months after OLT.Conclusions:ALSS treatment can improve general conditions of the patient before operation.OLT plus ALSS is one of the most effective therapies for acute-on-chronic failure patients.
Keywords:liver transplantation  artificial liver  severe hepatitis  liver failure
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