Risk factors for severe complications of the novel influenza A (H1N1): analysis of patients hospitalized in Italy |
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Authors: | M. Bassetti A. Parisini A. Calzi F.M. Bobbio Pallavicini G. Cassola S. Artioli M. Anselmo G. Pagano G. Rezza C. Viscoli |
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Affiliation: | 1. Infectious Diseases Division, San Martino Hospital and University of Genoa School of Medicine, Genoa;2. Intensive Care Unit, San Martino Hospital, Genoa;3. Infectious Diseases Division, EO Galliera, Genova;4. Infectious Diseases Division, S. Andrea Hospital, Spezia;5. Infectious Diseases Division, San Paolo Hospital, Savona;6. Infectious Diseases Division, S. Martino Hospital, Genova;7. Department of Infectious Diseases, Istituto Superiore di Sanità, Roma, Italy |
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Abstract: | Eighty-one patients affected by the novel influenza A (H1N1), hospitalized in North-western Italy, were studied. The median age was 32 years (range 1–81 years). Fifty-six (69%) had an underlying medical condition, including lung disorders (asthma or chronic obstructive pulmonary disease) in 34% and obesity in 25%. Fifty percent of them had pneumonia, 12% were admitted to the intensive care unit and 3% died. Antiviral treatment was initiated in 75% of patients started within 48 h. Older age and lung and neurocognitive disorders were associated with severe disease and death. |
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Keywords: | Complications H1N1 pneumonia risk factors |
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