Bioactive saponins from Dioscorea futschauensis |
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| Authors: | Liu H W Hu K Zhao Q C Cui C B Kobayashi H Yao X S |
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| Institution: | Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang, China. |
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| Abstract: | A new anti-neoplastic spirostanol saponin, (25S)-spirost-5-en-3 beta, 27-diol-3O-alpha-L-rhamnopyranosyl(1-->2)-beta-D-glucopyranosyl (1-->3)]-beta-D-glucopyranoside and three known compounds viz. prosapogenin A of dioscin, dioscin and gracilin were isolated from Dioscorea futschauensis by bioactivity-guided fractionation. Their structures were elucidated mainly by means of spectroscopic analysis. Their bioactivity against Pyricularia oryzae and cytotoxic activity on ts-FT210 cell line was evaluated. |
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