复明片对视网膜脱离复位术后视神经功能恢复的疗效

目的：评价中药复明片对视网膜脱离复位术后患者视神经功能恢复的疗效。 方法：采用分组对照研究的方法,将我院2010-01/2013-01收治的视网膜脱离复位术患者60例,根据治疗方法随机分为复明片治疗组（观察组）30例和甲钴胺注射液治疗组（对照组）30例。随访6wk,记录并对比分析两组患者视力、眼压、眼底情况以及视网膜神经纤维层厚度（ RNFLT）。 结果：观察组视力、眼底有效率分别为90%,97%,对照组分别为77%,80%,两组比较差异有显著统计学意义（ P〈0.01）。两组患者在治疗后暗适应和明适应ERG a、b波振幅及治疗前后暗适应和明适应a、b波振幅的差值有显著性意义（P〈0.05）,而眼压无明显统计学差异（P〉0.05）。 结论：复明片能促进视网膜复位术后视网膜下液体的吸收,促进视神经恢复,改善视功能。

Clinical therapeutic effect of Fuming tablet for optic nerve function recovery after retinal detachment surgery

AIM: To evaluate the Fuming tablet's clinical therapeutic effect on the recovery of optic nerve function after the retinal detachment surgery.

METHODS: Group control study was performed in 60 cases of retinal detachment surgery in our hospital from Jan 2010 to Jan 2013. According to different treatments, these patients were divided into different group. Thirty patients underwent Fuming tablet treatment(observation group),whereas others received mecobalamin injection treatment(control group). All of these patients were followed-up for 6wk. During these processes, we were recording and analyzing their visual acuity, intraocular pressure, ocular fundus condition and retinal nerve fiber layer thickness(RNFLT).

RESULTS: The effective rate of visual acuity and ocular fundus in observation group were 90% and 97% respectively, and in control group were 77% and 80% respectively. The difference had statistically significance.(P<0.01). Compared with control group, post-treatment a and b wave amplitude of observation group in dark adaptation and light adaptation have significant differences, as well as the difference of a and b wave amplitude in pre-treatment and post-treatment(P<0.05). But intraocular pressure had not significantly statistical differences(P>0.05).

CONCLUSION: Fuming tablet can improve the absorption of fluid under retina after retinal detachment surgery, the recovery of optic nerve and visual function.