| TC与MPV方案治疗晚期非小细胞肺癌的疗效观察 |
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| 引用本文： | 刘健,赵霞,何秋明,陈兆红,刘晓波,林芳,罗锋. TC与MPV方案治疗晚期非小细胞肺癌的疗效观察[J]. 华西医学, 2003, 18(4): 463-464 |
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| 作者姓名： | 刘健 赵霞 何秋明 陈兆红 刘晓波 林芳 罗锋 |
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| 作者单位： | 四川大学华西医院教育部人类疾病生物治疗重点实验室与肿瘤中心 四川成都610041(刘健，何秋明)，四川大学华西附二院 四川成都610041(赵霞)，四川省德阳市人民医院肿瘤科 四川德阳618000(陈兆红)，四川省德阳市第五人民医院肿瘤科 四川德阳618000(刘晓波)，四川省内江市第二人民医院肿瘤科 四川内江641000(林芳)，四川大学华西医院教育部人类疾病生物治疗重点实验室与肿瘤中心 四川成都610041(罗锋) |
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| 摘 要： | 目的 :比较TC与MPV方案治疗晚期非小细胞肺癌 (NSCLC)的疗效。方法 :80例晚期NSCLC患者采用TC4 0例 ,采用MPV4 0例 ,用Kaplan -Meier方法分析患者生存期。采用Cox比例风险模型分析影响预后的因素。结果 :MPV组中位生存期为 9个月 ,TC组中位生存期 14个月。两组生存期差异有显著性 (P <0 0 0 5 ,0 0 0 1) ,化疗的毒副反应主要是胃肠道反应和骨髓抑制。结论 :TC比MPV能延长患者生存期 ,但并没有增加毒副反应
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| 关 键 词： | TC MPV方案 治疗 晚期 非小细胞肺癌 疗效观察 |
| 文章编号： | 1002-0179(2003)04-0463-02 |
| 修稿时间： | 2003-09-02 |
Retrospective Comparison between TC and MPV Protocols for Advanced Non-small Cell Lung Cancer |
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| LIU Jian,ZHAO Xia,HE Qiu-ming,et al.. Retrospective Comparison between TC and MPV Protocols for Advanced Non-small Cell Lung Cancer[J]. West China Medical Journal, 2003, 18(4): 463-464 |
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| Authors: | LIU Jian ZHAO Xia HE Qiu-ming et al. |
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| Abstract: | Objective:To compare the theapeutic efficacy between TC and MPV protocols for advanced non-small cell lung cancer(NSCLC).Methods:Eighty patients having advanced non-small cell lung cancer,40 received TC and 40 received MPV.Kaplan Meier method was used for survival rate and Cox regression model for prognostic factors.Results:The overall median three-years survival time in the MPV group was 9 months,and 14 months in the TC group.The major toxic effects of the two groups were gastrointerstinal tract reactions and myelosuppression.Conclusion:TC chemotherapy can prolong the survival time more in patients with advanced NSCLC than MPV chemotherapy but without increasing its toxicity. |
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| Keywords: | Lung neoplasms/drug therapy Carcinoma non-small cell/drug therapy TC protocol MPV protocol |
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