口服曲马多辅助丙泊酚无痛人流术效果观察

目的观察口服曲马多缓释片辅助丙泊酚无痛人工流产术的麻醉效果。方法早孕妇女80例,随机分为两组（n=40）：口服曲马多辅助丙泊酚组（PT组）和丙泊酚（P组）。PT组予术前1h口服盐酸曲马多缓释片100mg（1片）。两组均按丙泊酚2.0mg/kg诱导,术中维持每次追加丙泊酚0.5～1.0mg/kg,记录丙泊酚用量、意识恢复、自由对答和自行离去时间、呼吸和循环监测指标、苏醒期有无宫缩痛及疼痛程度（VAS评分）。结果两组注射丙泊酚麻醉诱导后1min的MAP和SpO2明显降低（P〈0.05）,但均在正常范围,组间比较无明显差别（P〉0.05）;PT组丙泊酚用量明显少于P组（P〈0.05）;PT组丙泊酚注射痛和术后宫缩痛明显低于P组（P〈0.05）,PT组呼吸抑制发生率明显低于P组（P〈0.05）。结论无痛人工流产术病人,术前口服曲马多缓释片可减少丙泊酚麻醉用药量,减轻丙泊酚注射痛,降低呼吸抑制和术后宫缩痛发生率。

Effect of propofol combined with tramadol on induced abortion

Objective To investigate the clinical effect of propofol combined with oral trmadol hydrochoride sustained-release tablet on induced abortion.Methods 80 pregnant women were randomly divided into 2 groups:the propofol combined with trmadol group(PT group)and the propofol group(P group).The cases were respectively administered with oral tramadol hydrochloride sustained-release tablet 100 mg(1 table) 1 hours before operation in the PT group.And then anesthesia was induced with propofol 2 mg/kg in all cases,and...