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Early postoperative delirium after open-heart cardiac surgery is associated with decreased bispectral EEG and increased cortisol and interleukin-6 |
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| Authors: | Konstanze Plaschke Philipp Fichtenkamm Christoph Schramm Steffen Hauth Eike Martin Markus Verch Matthias Karck Jürgen Kopitz |
| Affiliation: | (1) Department of Anesthesiology, University of Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany;(2) Department of Pathology, University of Heidelberg, Im Neuenheimer Feld 220, 69120 Heidelberg, Germany;(3) Department of Cardiac Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany |
| Abstract: | PurposeIt is difficult to substantiate the clinical diagnosis of postoperative delirium with objective parameters in intensive care units (ICU). The purpose of this study was to analyze (1) whether the bilateral bispectral (BIS) index, (2) cortisol as a stress marker, and (3) interleukin-6 as a marker of inflammation were different in delirious patients as compared to nondelirious ones after cardiac surgery. |
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