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慢性肾小球疾病神经电生理研究
引用本文:侯明,管益君,胡昭,蒋捍东,靖新文,王秀琴,唐占府. 慢性肾小球疾病神经电生理研究[J]. 山东大学学报(医学版), 1993, 0(2)
作者姓名:侯明  管益君  胡昭  蒋捍东  靖新文  王秀琴  唐占府
作者单位:附属医院内科,附属医院内科,附属医院内科,附属医院内科,附属医院内科,附属医院内科,附属医院内科
摘    要:对90例慢性肾小球疾病病人(慢性肾炎56例、慢性肾功能衰竭34例)及16例终末期肾衰病人腹膜透析治疗前后进行体感诱发电位、脑干听觉诱发电位及视觉诱发电位的同步监测。慢性肾炎尤其慢性肾功能衰竭时,体感、听觉及视觉诱发电位诸波潜伏期均较正常对照组显著延长(P<0.05~0.01),其异常程度与肾功能密切相关,经腹膜透析治疗后,肾衰病人诱发电位异常随肾功能改善可有不同程度的好转。诱发电位综合检查可作为早期发现肾小球疾病病人神经系统异常的灵敏指标。

关 键 词:肾炎  肾功能衰竭  慢性  诱发电位  躯体感觉  诱发电位  听觉  诱发电位  视觉

NEURO-PHYSIOLOGICAL STUDY ON CHRONIC GLOMERULAR NEPHROPATHIES
Hou Ming,et al Dept.of Internal Medicine,the Affiliated Hospital of Shandong Medical University. NEURO-PHYSIOLOGICAL STUDY ON CHRONIC GLOMERULAR NEPHROPATHIES[J]. Journal of Shandong University:Health Sciences, 1993, 0(2)
Authors:Hou Ming  et al Dept.of Internal Medicine  the Affiliated Hospital of Shandong Medical University
Abstract:Parameters of renal function,somatosensory evoked potentials(SEPs),brain-stem auditory evoked potentials(BAEPs),and visual evok-ed potentials(VEPs)were measured synchronously in 90 cases of chronicglomerular nephropathy patients(including 56 cases of chronic glomerularnephritis and 34 cases of chronic renal failure).Prolonged latencies of SEPs,BAEPs,and VEPs were generally noticed in chronic glomerular nephropa-thies,esp.in chronic renal failure.Abnormal evoked potentials might beimproved after peritoneal dialysis in renal failure patients.The SEP N3pland BAEP V pl were negatively correlated with hemoglobin level and plasmaalbumine level respectively.The incidence of SEP(N3)abnormalities andthe VEP P100 pl were proportional to BUN and blood creatinine levels inCRF patients.Multiple evoked potentials measurement might be consideredas a sensitive approach in early diagnosis of neuropathies in chronic glo-merular nephropathies.
Keywords:Nephritis  Kidney failure  chronic  Evoked potentials  somatosensory  Evoked potentials  auditory  Evoked potentials  visual
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