重症肺部感染经纤维支气管镜支气管肺泡灌洗治疗临床观察

目的探讨经纤维支气管镜肺泡灌洗治疗重症肺部感染的临床价值及其疗效。方法将104例重症肺部感染患者随机分为纤支镜组及常规组各52例,常规组给予抗感染、吸氧、雾化吸入、体位引流、鼻导管吸痰、营养支持、纠正电解质紊乱等常规措施治疗,纤支镜组在以上常规治疗基础上加用纤维支气管镜肺泡灌洗治疗,观察症状缓解情况及治疗10 d时评价两组治疗疗效。结果患者咳嗽消失时间、咳痰消失时间、体温恢复时间、白细胞恢复正常时间及住院时间纤支镜组明显短于常规组,比较差异具有统计学意义(P<0.05);纤支镜组治疗总有效率98.08%,常规组总有效率75.00%,比较差异具有统计学意义(P<0.05);纤支镜组灌洗后明显较灌洗前PH值、PaO2、PaCO2得到改善,比较差异具有统计学意义(P<0.05)。结论对于重症肺部感染患者采取经纤维支气管镜肺泡灌洗能明显提高治疗疗效,减少住院时间。

Clinical observation of bronchoalveolar lavage through fiber bronchoscopy in the treatment of patients with severe pulmonary infection

Objective To investigate its clinical value and curative effect of bronchoalveolar lavage through fiber bronchoscopy in the treatment of patients with severe pulmonary infection. Methods 104 patients with severe pulmonary infection were randomly and e- venly divided into two groups. All patients were given the conventional treatment, which included anti - infection, oxygen uptake, atomi- zation inhalation, postural drainage, nasal catheter sputum aspiration, nutritional support, and electrolyte disorder correction. The treat- ment group was additionally given broncboalveolar lavage through fiber bronchoscopy. The curative effect was compared between the two groups 10 days after the treatment. Results The duration of cough disappeared, expectoration disappeared, body temperature back to normal, leucocyte back to normal and hospital stay was obviously shorter in the treatment group than in the control group with statistical significance （ P 〈 0.05 ）. The total effective rate was 98.08% in the treatment group and 75.00% in the control group （ P 〈 O. 05 ）. The improvement of PH value, PaO2 , and PaCOz was more pronounced in the treatment group than in the control group （ P 〈 0.05 ）. Conclu- sion Bronchoalveolar lavage through fiber bronchoscopy can significantly improve the curative effect and reduce the duration of hospital stay in the treatment of patients with severe pulmonary infection.