佐匹克隆联合针灸治疗原发性失眠症对照研究

目的探讨佐匹克隆联合中医针灸治疗原发性失眠症的临床效果。方法将62例原发性失眠症患者随机分为治疗组30例，对照组32例，两组均口服佐匹克隆治疗，治疗组联合中医针灸治疗，观察4周。采用匹兹堡睡眠质量指数、汉密顿抑郁量表、汉密顿焦虑量表、副反应量表进行测评分析。结果治疗后两组匹兹堡睡眠质量指数总分较治疗前显著下降（P〈0．01）；治疗4周末治疗组匹兹堡睡眠质量指数总分显著低于对照组（P〈0．05）。结论佐匹克隆联合针灸治疗原发性失眠症患者能显著提高临床疗效，优于单用佐匹克隆治疗。

A control study of zopiclone combined with acupuncture in primary insomnia

Objective To explore the efficacy of zopiclone combined with acu- puncture in primary insomnia. Methods Sixty-two patients with primary insomnia were randomly assigned to treatment （n：30） and control group （n=32）,both groups took orally zopiclone, and treatment group was plus acupuncture for 4 weeks. Assessments were conducted with the Pittsburgh Sleep Quality Index （PSQI）, Hamilton Depression Scale （HAMD）, Hamilton Anxiety Scale （HAMA） and Treatment Emergent Symptom Scale （TESS）. Results The total scores of the PSQI of both groups lowered more significantly after treatment compared with pretreatment （P〈0.01） ; at the end of the 4th week the total score of the PSQI was significantly lower in treatment than control group （P〈0.05）. Conclusion Zopiclone combined with acupuncture in primary insomnia could improve clinical efficacy notably compared with single zopiclone.