| Abstract: | A series of 156 cases of meibomirm gland
carcinomas are studied pathologically with 100
cases followed up. This represents the Iargest
series of original cases so far reported in the
literature availahle to us. This' tumor is ap-
parcntly one of the most mabgnant trimors of
the eyelids as ewdenced both by lymphatic
spread and hlood-horne metastasis, resulting
in a high mortality rate of 41%.
The histologic structure of the tumor is ex-
tremely variable. It may simulate squamous
cell carcinoma, basal cell carcinoma, adenocar-
cinoma or spindle cell carcinamu.s. Therefore
in dealing with the large numher of cases in
our ophthalmic clinic, we have evolved a tenta-
tive pathologic classification of thfs tumor into
5 different types: the diftereatiated, squamous
cell, basaI cell, adcnold and spindle cell.
According to the follow-up data of 100
cases, the pathalogic classification appears to
have some bcaring UPOn its clinical manifesta-
tions, the differentiated type heing the least
maiignane, while tbe basal cell and squamous
cell types are the most malignant.
Cases of the adenoled type and spindle cell
type are too few to warrant any COPclusions
concerning their clinical manifestations. |
