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Molecular typing of methicillin-susceptible Staphylococcus aureus isolates collected in the Yogyakarta area in Indonesia, 2006
Authors:R. H. Deurenberg  P. S. Beisser  M. J. Visschers  C. Driessen   E. E. Stobberingh
Affiliation:Department of Medical Microbiology, Maastricht University Medical Center, Maastricht, The Netherlands
Abstract:The characterization of 62 community-associated methicillin-sensitive Staphylococcus aureus (MSSA) isolates from 440 individuals in the Yogyakarta area of Indonesia in 2006 showed that: (i) almost half of the isolates were associated with methicillin-resistant S. aureus lineages [clonal complex (CC)1, CC8 and CC45] and (ii) ten Panton–Valentine leukocidin-positive isolates were associated with CC1 ( n  = 7), CC30 ( n  = 1) and CC51 ( n  = 2). The high Panton–Valentine leukocidin prevalence (16%) among S. aureus is of concern because these strains can cause severe infections and the introduction of staphylococcal cassette chromosome mec into virulent and epidemic MSSA could pose a serious public health threat.
Keywords:Antibiotic resistance    community    Indonesia    PVL    S. aureus    spa typing
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