胆道支架置放治疗恶性梗阻性黄疸的预后因素分析

目的　探讨胆道支架置放治疗恶性梗阻性黄疸的预后因素。方法　 71例恶性梗阻性黄疸患者放置胆道支架后 ,选择性别、年龄、肿瘤类型、术前血清胆红素浓度、梗阻时间、梗阻水平、梗阻长度以及是否结合动脉化疗栓塞和 (或 )化疗灌注术 (TAE和 (或 )TAI)等 13个因素作为研究对象 ,进行单因素和多因素分析。结果　单因素分析显示肿瘤类型、梗阻水平以及是否结合TAE和 (或 )TAI对预后有显著影响 ,多因素分析显示是否结合TAE和 (或 )TAI术是影响预后的主要因素。结论　恶性梗阻性黄疸患者放置支架后 ,进行TAE和 (或 )TAI术可以延长生存期。

Predictive Factors for the Treatment of Malignant Obstructive Jaundice with Biliary Stent

Purpose To define predictive factors for the treatment of malignant obstructive jaundice(MOJ) with biliary stent. Methods Univariate and multivariate analysis were performed in seventy-one patients with MOJ who had been treated with biliary stent.Thirteen factors including gender,age,preoperative serum bilirubin level,tumor classification,duration of obstruction,obstructuve level,obstructive length,whether transcatheter arterial chemo-embolization and/or chemo-infusion(TAE and/or TAI) having been performed were studied. Results In univariate analysis the variables associated with survival were tumor classification,obstructive level,whether TAE and/or TAI having been performed.By multivariate analysis,TAE and/or TAI was the independent prognostic factor. Conclusions Biliary stent implantation combined with TAE and/or TAI in treating patient with MOJ may prolong survival.