胸腹腔积液四项指标联合检测的意义

目的:探讨胸腹腔积液pH、CEA、LDH、GLU水平联合检测在良、恶性胸腹腔积液中的临床鉴别诊断意义。方法:设立结核性胸膜炎组和非特异性炎症组及恶性肿瘤组,检测所有患者胸腹腔积液中pH、CEA、LDH、GLU的浓度,检测结果采用方差分析和DunettC法进行统计分析。结果:恶性组患者胸腹腔积液标本中pH、CEA值较结核性胸膜炎组和非特异性炎症组明显升高(P<0.05);恶性组和结核性胸膜炎组标本LDH值之间差异无显著性(P>0.05)但均高于慢性非特异性炎症组(P<0.05);恶性组和非特异性炎症组标本GLU值差异无显著性(P>0.05)但均高于结核性胸膜炎组(P<0.05),结论:联合检测pH、CEA、LDH及GLU对胸腹腔积液性质的鉴别诊断有重要临床参考价值。

Significance of Combined Detection of pH、CEA 、LDH And GLU Levels for Pleural/ascitic Fluid

Objective To explore the significance of combined detection of pH、CEA、LDH and GLU Levels for the distinguishing diagnosis of carcinoid and malignant pleural /ascitic fluid.Methods Pleural/ascitic fluid were extracted from benign and malignant tumors respectively and figures metioned above were detected.Results pH and CEA values in the samples with malignant tumor was remarkably increased compared with tuberculous or chronic nonspecific inflammation(P<0.05).The LDH values in the samples from the malignant tumor and the tuberculous pleuritis did not show difference(P>0.05),but higher than that from the chronic nonspecific inflammation(P<0.05).The Glu values in the samples from the malignant tumor and the chronic nonspecific inflammation was similar(P>0.05).but higher than that from the tuberculous pleuritis(P<0.05).Conclusion Combined detection of pH、CEA、 LDH and GLU may be a useful method for the distinguishing diagnosis of carcinoid and malignant tumors.