The safety, tolerability and effectiveness of generic antiretroviral drug regimens for HIV-infected patients in south India |
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Authors: | Kumarasamy Nagalingeswaran Solomon Suniti Chaguturu Sreekanth K Mahajan Anish P Flanigan Timothy P Balakrishnan P Mayer Kenneth H |
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Affiliation: | YRG Centre for AIDS Research and Education, Chennai, India. |
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Abstract: | We investigated the safety, tolerability and effectiveness of locally produced generic highly active antiretroviral therapy (HAART) regimens with a chart review conducted at YRG CARE, a tertiary HIV referral centre in India. A total of 333 patients had been on Indian-manufactured generic HAART for at least 3 months. In this cohort, generic HAART was safe, well tolerated and effective at increasing CD4 T-lymphocyte counts in patients with advanced HIV, comparable to the experience with proprietary HAART. |
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