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紫杉醇/顺铂联合同步放疗治疗晚期非小细胞肺癌的疗效
引用本文:王海荣,周强,董华琼,刘黎.紫杉醇/顺铂联合同步放疗治疗晚期非小细胞肺癌的疗效[J].中国实用医药,2010,5(19):9-10.
作者姓名:王海荣  周强  董华琼  刘黎
作者单位:遂宁市中心医院肿瘤科,629000
摘    要:目的观察紫杉醇/顺铂联合同步放疗治疗晚期非小细胞肺癌的疗效及安全性。方法紫杉醇60mg/m^2 dl,8,15,顺铂30mg/m^2,dl,8,15,28天为一周期,同时适当水化,预防胃肠道反应,共化疗3~6周期。每周期化疗前12h和3h同时服用地塞米松7.5mg和雷尼替丁0.15g。同步放疗的方案是每天1.8~2Gy,每周5d,总放疗量是64—70Gy/6.5—7周。结果20例中有4例(20%)获得CR,8例(40%)获得PR,OOR为60%。结论紫杉醇/顺铂联合同步放疗治疗晚期非小细胞肺癌是有效的,有一定的毒副作用,但是可以耐受。

关 键 词:紫杉醇/顺铂  同步放疗  晚期非小细胞肺癌

The curative effect of Taxol and Cisplatin concomitant with thoracic radiation therapy for patients with adwanced non-small-cell lung cancer
WANG Hai-rong,ZHOU Qiang,DONG Hua-qiong,et al..The curative effect of Taxol and Cisplatin concomitant with thoracic radiation therapy for patients with adwanced non-small-cell lung cancer[J].China Practical Medical,2010,5(19):9-10.
Authors:WANG Hai-rong  ZHOU Qiang  DONG Hua-qiong  
Institution:WANG Hai-rong,ZHOU Qiang,DONG Hua-qiong,et al.Department of tumour,Suining Central Hospital,Suining 629000,China
Abstract:Objective Be observedthe curative effect and security of mostly project of Taxol and Cisplatin concomitant with thoracic radiation therapy for patients with adwanced non-small-cell lung cancer.Methods Ttaxol 60 mg/m2 d1,8,15 ivgtt;cisplatin 30 mg/m2 ivgtt d1,8,15,pay a great lot of water propnety at one time,defend reactivity of gastric intestines.One cycle is 28 day.For therapy 3-6cycles.At one time pay DXM 4.5 mg and Ranitidine 0.15 g befor chemotherapy 12 h and 3 h.In-phase radiation therapy 1.8-2 Gy eve...
Keywords:Taxol/Cisplatin  Thoracic radiation therapy  Non-small-cell lung cancer  
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