Synthesis and biological evaluation of pyrrole-2-carboxamide derivatives: oroidin analogues |
| |
Authors: | Balaram S. Takale Neha V. Desai Afsar Ali Siddiki Hemchandra K. Chaudhari Vikas N. Telvekar |
| |
Affiliation: | 1. Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Matunga, Mumbai, 400 019, India
|
| |
Abstract: | The reaction of pyrrole or dibromopyrrole-2-trichloroacetone with various amines results in the series of novel pyrrole-2-carboxamide bearing aromatic heterocycle or aryl or alkyl groups. Synthesized molecules were evaluated for their in vitro antibacterial activities. Most of the compounds exhibited potent activity against both Gram-positive and negative pathogens. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |