| 严重急性呼吸综合征(SARS)患者血清超氧化物歧化酶含量测定及其临床意义 |
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| 引用本文： | 叶一秀,王巍,李洪敏,王仲元,孙立群,王安生,李楠,郭晓青,姚昊,刘金伟,陈红兵,林明贵,王金河,周历.严重急性呼吸综合征(SARS)患者血清超氧化物歧化酶含量测定及其临床意义[J].标记免疫分析与临床,2003,10(3):136-138. |
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| 作者姓名： | 叶一秀 王巍 李洪敏 王仲元 孙立群 王安生 李楠 郭晓青 姚昊 刘金伟 陈红兵 林明贵 王金河 周历 |
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| 作者单位： | 解放军第309医院,北京,100091 |
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| 摘 要： | 为观察SARS患者血清超氧化物歧化酶(SOD)含量变化，本文采用RIA检测了66例SARS患者血清SOD含量，并与对照组比较。患者SOD含量明显低于对照组，重型的SARS患者SOD含量明显低于普通型的。恢复期患者SOD含量回升，但仍低于对照组。SARS患者体内产生过量的自由基，使SOD过度消耗。SOD含量变化可以反映SARS病情的严重程度。为此，检测血清SOD有助于观察病情的变化。采用清除机体自由基的药物可能是一种治疗措施。
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| 关 键 词： | 严重急性呼吸综合征 SARS 血清 超氧化物歧化酶 含量 测定 |
| 文章编号： | 1006-1703(2003)03-0136-03 |
| 修稿时间： | 2003年7月4日 |
The Measurement of Superoxide Dismutase in Patients with Severe Acute Respiratory Syndrome and Its Clinical Significance |
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| YE Yi-xiu,WANG Wei,LI Hong-min,et al..The Measurement of Superoxide Dismutase in Patients with Severe Acute Respiratory Syndrome and Its Clinical Significance[J].Labeled Immunoassays and Clinical Medicine,2003,10(3):136-138. |
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| Authors: | YE Yi-xiu WANG Wei LI Hong-min |
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| Abstract: | To study the clinical significance of serum SOD in patients with severe acute respiratory syndrome(SARS),the level of serum SOD in 66 patients with SARS was measured by RIA and compared with control group.The results showed that the level of serum SOD in patients with SARS was significantly lower than that in control group.The serum SOD level in severe type of patients was lower than that in general type.The serum SOD level in convalescent patients was increased,but still lower than that in control group.There were excessively free radicals in patients with SARS,so SOD was depleted excessively.The change of SOD in patients with SARS maybe reflect the severe degree of ill.Dynamic detection of serum SOD level was helpful in analyzing serious or mild SARS.It may be an important therapeutic measure that excessively free radicals were eliminated from the body. |
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| Keywords: | Severe acute respiratory syndrome(SARS) Superoxide dismutase RIA |
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