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| 儿童恶性血液病并发毛细血管渗漏综合征的危险因素分析 | |
| 引用本文： | 任颖,刘述,杨月明,刘洪军.儿童恶性血液病并发毛细血管渗漏综合征的危险因素分析[J].南方医科大学学报,2015,35(4):606-609. |
| 作者姓名： | 任颖 刘述 杨月明 刘洪军 |
| 作者单位： | 1. 皖南医学院附属弋矶山医院儿科,安徽 芜湖,241001 2. 中山大学中山医学院人体解剖教研室,广东 广州,510080 3. 大连市妇女儿童医疗中心儿童血液肿瘤科,辽宁 大连,116000 4. 安徽医科大学附属安徽省立医院儿科,安徽 合肥,230001 |
| 基金项目： | 广东省自然科学基金(S2012010009215) |
| 摘 要： | 目的探讨儿童恶性血液病并发毛细血管渗漏综合征（CLS）发生的危险因素，提高对儿童恶性血液病并发毛细血管渗漏 综合征的临床认识。方法采用30例儿童恶性血液病发生CLS患儿的临床资料，对CLS发生的高危因素进行多元logistic回归 分析。结果在0.05检验水准下，有无低氧血症，有无败血症与应变量之间的联系有统计学意义，CLS前白细胞数目，有无严重 骨髓抑制在检验水准附近。结论毛细血管渗漏综合征为儿童恶性血液病治疗过程中的少见急重症，低氧血症和败血症是儿童 恶性血液病并发CLS的危险因素，儿内科医师应引起重视。 |
| 关 键 词： | 儿童恶性血液病 毛细血管渗漏综合征 危险因素 |
Risk factors for capillary leak syndrome in children with hematological malignancies |
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| REN Ying , LIU Shu , YANG Yueming , LIU Hongjun.Risk factors for capillary leak syndrome in children with hematological malignancies[J].Journal of Southern Medical University,2015,35(4):606-609. | |
| Authors: | REN Ying LIU Shu YANG Yueming LIU Hongjun |
| Institution: | REN Ying;LIU Shu;YANG Yueming;LIU Hongjun;Department of Pediatrics, Yijishan Hospital, Wannan Medical College;Department of Anatomy, Sun Yatsen University;Department of Pediatric Hematological Oncology,Women and Children’s Medical Center;Department of Pediatrics, Anhui Provincial Hospital; |
| Abstract: | Objective To investigate the risk factors for capillary leak syndrome (CLS) in children with malignant hematologic diseases. Methods Thirty children with hematological malignancies complicated with CLS were analyzed with multiple logistic regression analysis. Results At the test level of 0.05, hypoxemia and septicemia were found to significantly correlate with CLS in these children, and the number of white blood cells before CLS and severe bone marrow suppression were near the test level. Conclusion Hypoxemia and septicemia are risk factors for CLS in children with malignant hematologic diseases. |
| Keywords: | children malignant hemopathy capillary leak syndrome risk factors |
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