吉林省长春市老年人2型糖尿病及糖调节受损患病现况及影响因素分析

目的:了解吉林省长春市老年人2型糖尿病(T2DM)和糖调节受损(IGR)的患病情况,探讨其影响因素,为糖尿病的防治提供依据。方法:采用分层随机整群抽样的方法,采取问卷调查与体格检查相结合的方式,收集吉林省长春市6个社区60岁及以上常住居民的849份有效问卷。根据1999年WHO糖尿病及IGR的诊断标准并结合自报情况将被调查者分为糖调节正常组(NGR,n=541)、IGR(n=150)组和T2DM(n=158)组。比较各组研究对象的身高、体质量(BMI)、血压、血糖和血脂水平。采用多因素Logistic回归分析T2DM的可能影响因素。结果:吉林省长春市60岁及以上老年人IGR患病率为17.7%;T2DM患病率为18.6%;男性IGR患病率及T2DM患病率与女性比较差异均无统计学意义(P<0.05)。NGR、IGR和T2DM组患者收缩压(SBP)、舒张压(DBP)、BMI和甘油三酯(TG)水平比较差异均有统计学意义(P<0.05)。IGR组患者血清TG高于NGR组(P<0.05);T2DM组患者SBP和BMI水平高于IGR组(P<0.05);T2DM组患者SBP、DBP、BMI和TG水平高于NGR组(P<0.05)。多因素Logistic回归分析,BMI可能是T2DM的影响因素。结论:吉林省长春市60岁及以上老人IGR与T2DM的患病率均较高;IGR者已出现了部分生化指标改变,BMI可能会增加糖尿病发生的风险。对于60岁以上老人,应采取综合性措施防治糖尿病的发生,降低其患病率。

Analysis on condition and influencing factors of T2DM and IGR of elderly in Changchun city in Jilin province

Objective To investigate the prevalence of type 2 diabetes(T2DM)and impaired glucose regulation(IGR) in Changchun city in Jilin province,and to analyze its influencing factors and provide the evidence for the prevention and treatment of T2DM. Methods 847 elderly aged over 60 from six districts of Changchun city in Jilin province were selected by multistage stratified random cluster sampling method.The investigation was conducted by the combination of questionnaire and physical examinations.According to the 1999 diagnosis criteria of WHO and self-report,the citizens were divided into normal glucose tolerance group(NGR,n=541),impaired glucose regulation group (IGR,n=150),and type 2 diabetes mellitus group(T2DM,n=158).The levels of height,body mass index(BMI),blood pressure,blood glucose,and blood lipid of the objects in various groups were compared.Maltivariate Logistic regression was carried out to analyze the influencing factors of T2DM. Results The prevalence rates of IGR and T2DM were 17.7% and 18.6% respectively in the people aged over 60 years in Changchun city in Jilin province;the prevalence rates in male with IGR and T2DM had no significant difference compared with those in female(P>0.05);there were significant differences in the SBP,DBP,BMI,and TG levels of the objects between NGR,IGR,and T2DM groups(P<0.05);the level of TG of the objects in NGR group was higher than that in IGR group(P<0.05).Both the SBP and BMI of the objects in T2DM group were higher than those in IGR group(P<0.05).The SBP,DBP,BMI,and TG levels of the objects in T2DM group were higher than those in NGR group(P<0.05).The multivariate Logistic regression results showed that BMI may be the influencing factor of T2DM. Conclusion The prevalences of IGR and T2DM are high in the citizens aged over 60 in Changchun city in Jilin province;some biochemistry indexes are abnormal in the stage of IGR,and BMI may increase the risk of diabetes.We should take comprehensive measures to control the incidence of diabetes and reduce the prevalence.