启闭通关汤治疗良性前列腺增生症33例疗效观察

目的　观察自拟启闭通关汤治疗老年良性前列腺增生症 (BPH)的临床疗效。方法　 6 2例BPH患者随机分为 2组。治疗组 33例 ,用自拟启闭通关汤治疗 ;对照组 2 9例 ,用保列治片治疗。 2组均 1个月为 1个疗程 ,3个疗程结束后判断疗效 ,并分别于治疗前和治疗 1、3个疗程时观察记录前列腺症状评分 (IP SS)、生活质量评分、前列腺体积、最大尿流率、残余尿量变化。结果　 2组在治疗 1个疗程时IPSS和生活质量评估均有明显改善 ,治疗 3个疗程较治疗 1个疗程时又有明显改善。治疗 1个疗程时 ,治疗组的最大尿流率已有明显改善 ,残余尿量明显减少 (P <0 .0 5 ) ,但前列腺体积缩小不明显 ,对照组变化均不显著 ,治疗 3个疗程时 ,2组的前列腺体积均明显缩小 (P <0 .0 1)。治疗组总有效率为 81.82 %,对照组为 6 8.97%,治疗组疗效明显优于对照组 (P <0 .0 1)。结论　自拟启闭通关汤能提高最大尿流率 ,减少残余尿量 ,使部分患者的前列腺体积明显缩小 ,未见明显毒副作用 ,综合疗效优于对照组。

Therapeutic effect of Qibitongguan decoction on 33 cases of benign prostatic hypertrophy

Objective To investigate the therapeutic effect of Qibitongguan decoction on benign prostatic hypertrophy (BPH) in the elderly. Methods 62 patients with BPH were randomly divided into two groups. 33 patients in treatment group were treated by Qibitongguan decoction; 29 patients in control group were treated by proscar tablets, with a treatment course of one month for both groups. The therapeutic effect was evaluated after three treatment courses. The international prostatic syndrome score (IPSS),life quality score, prostate volume, uroflowmetry (Qmax) and residual urine were recorded and analyzed before treatment and after one treatment course and three treatment course. Results The IPSS and life quality score of both groups were improved significantly after treatment, as compared with those before treatment. The Qmax and residual urine of treatment group were improved after one treatment course, but prostate volume was decreased slightly. The total effective rate in treatment group (81.82%) was obviously higher than that in control group (68.97%, P<0.05).Conclusion Qibitongguan decoction is effective in treating benign prostatic hypertrophy in the elderly.