61例恶性胸腺瘤患者治疗分析

目的：探讨恶性胸腺瘤的治疗方法及其疗效。方法：回顾分析61例恶性胸腺瘤的临床资料。按治疗方法分为完全切除组32例，部分切除组26例和探查组3例，每组中均有放疗和非放疗患者。以术后5年复发率和生存率做为疗效指标进行分析。结果：术后放疗患者5年复发率低于同组未放疗患者，5年存活率高于未放疗患者，大部切除结合放疗组与完全切除结合放疗组的5年复发率（P=0．926），生存率（88．9％VS86．4％）之间无显著差异。结论：胸腺恶性肿瘤因浸润性生长，多不能完全切除，术后结合放疗有助于控制局部复发和提高存活率。

Treatment of 61 cases with malignant thymoma

Objective：To study the treatment and therapeutic effect of malignant thymoma. Methods： The clinical data of 61 cases with malignant thymoma were analyzed retrospectively. All the patients were divided into three groups according to the surgical treatment：complete excision group （32 cases）, partial excision group （26 cases） and explo- ration group （3 cases）. The post operatively therapeutic effects were evaluate based on recurrence rate and survival rate. Results： Comparing the patients treated with radiotherapy to patients without radiotherapy, the foremer had a lower five - year relapse rate and a higher five - year survival rate. However, there is no significant difference between completely excised patients and partially excised patients in 5 - year relapse rate （ P = 0. 926） and 5 - year .cumulative survival rate （88.9% vs 86.4% ）with radiotherapy. Conclusion： Being infiltrative growth and high radio - sensitivity, the malignant thymoma is hard to be excised completely. The surgical treatment combined with postopera- tive radiotherapy is helpful to improve the 5 -years survival and control recurrence.