肠易激综合征患者近端胃舒张和排空功能的研究

背景：实时B超检查测量近端胃舒张和排空功能在胃肠动力障碍性疾病中的应用已越来越受到临床工作者的关注。目的：探讨腹泻型肠易激综合征（D-IBS）和便秘型肠易激综合征（C-IBS）患者近端胃舒张和排空功能的改变。方法：D-IBS患者、C-IBS患者和健康志愿者各20例，以实时B超检查测定饮用标准营养液（500ml）后不同时间点近端胃容积的变化。结果：D-IBS组、C-IBS组和对照组之间胃底气体评分无显著差异。D-IBS组除试餐后5、60min以及C-IBS组除试餐后60min外。其余时间点两组近端胃容积均显著低于对照组。D-IBS组与C-IBS组0min时近端胃容积和最大近端胃容积均显著低于对照组。D-IBS组所有时间点的近端胃容积与C-IBS组无显著差异。D-IBS组、C-IBS组的胃延迟排空相与对照组无显著差异。D-IBS组近端胃液体半排空时间（T1/2）较对照组显著提前，C-IBS组T1/2与对照组无显著差异。结论：IBS患者近端胃舒张功能受损，但D-IBS与C-IBS间无差异，IBS患者的近端胃排空加快。

Study on Accommodation and Emptying of Proximal Stomach in Patients with Irritable Bowel Syndrome

Background:The application of real-time B-type ultrasonography to investigate the accommodation and emptying of proximal stomach in the gastrointestinal disorders has received much concern among the clinicians.Aims:To investigate the changes of accommodation and emptying of proximal stomach in cases of irritable bowel syndrome with diarrhea(D-IBS) or constipation(C-IBS).Methods:20 D-IBS,20 C-IBS and 20 healthy controls were included.The changes of volume of proximal stomach were investigated by real-time B-type ultrasonography after drinking nutritious meal(500 ml) in different time points.Results:No significant differences were found between the air pockets score in D-IBS group,C-IBS group and the control group.After the test meal,the volume of proximal stomach of the time points in both D-IBS group(except 5,60 min) and C-IBS group(except 60 min) were all lower than those in the control group.Both the volume of proximal stomach at 0 min and maximum volume of proximal stomach in D-IBS group and C-IBS group were lower than those in the control group.In all eight time points,no significant differences were found between the volumes of proximal stomach in D-IBS group and C-IBS group.There was no significant difference in the lag phase of proximal stomach emptying between D-IBS group,C-IBS group and the control group.The proximal stomach half-emptying time in D-IBS group was markedly in advance of the control group,but no significant difference was found between C-IBS group and the control group.Conclusions:IBS patients have impaired accommodation of proximal stomach,but no difference is found between D-IBS and C-IBS.The emptying of proximal stomach in IBS patients is accelerated.