Long-term survival after Kasai's operation for biliary atresia |
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Authors: | Barbara A Stewart Roberta J Hall Frederick M Karrer John R Lilly |
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Institution: | (1) Department of Surgery, University of Colorado School of Medicine, 4200 East Ninth Avenue, C 314, 80262 Denver, CO, USA |
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Abstract: | Long-term survival of biliary atresia patients after Kasai hepaticoportoenterostomy is being increasingly reported. Prognostic factors indicative of a favorable long-term outcome consist of: (1) early age at operation; (2) bilirubin excretion of at least 6 mg daily 1 month after operation; (3) favorable hepatic histology at the time of operation; and (4) low incidence of postoperative cholangitis. Jaundice-free long-term survival is now attained in from one-fourth to one-third of patients undergoing Kasai hepaticoportoenterostomy by experienced surgeons in the Western hemisphere. In many long-term survivors there is normalization of liver function, improvement in hepatic histology, and resolution of the complications of portal hypertension. Most patients in this category have made a normal adjustment to their disease and lead active adolescent and adult lives.
Offprint requests to: B. A. Stewart |
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Keywords: | Biliary atresia Kasai hepaticoportoenterostomy |
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