| 红曲抗炎机制研究 |
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| 引用本文： | 王炎焱,赵征,黄烽,任建平.红曲抗炎机制研究[J].中国药物与临床,2006,6(5):350-352. |
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| 作者姓名： | 王炎焱 赵征 黄烽 任建平 |
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| 作者单位： | 1. 100853,北京,解放军总医院风湿科
2. 解放军军事医学科学院二所 |
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| 摘 要： | 目的研究红曲的抗炎机制。方法角叉菜胶致大鼠背部气囊滑膜炎模型,测定渗出液液体量,渗出液中白细胞(WBC)计数、C反应蛋白(CRP)、丙二醛(MDA)含量及血清CRP、MDA含量。结果红曲能明显减少渗出液体量,降低灌洗液中WBC、CRP、MDA含量和血清中CRP、MDA含量。结论红曲抗炎机制与抑制炎性因子的渗出,降低CRP含量及消除自由基、抑制脂质过氧化有关。
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| 关 键 词： | 红曲霉属 抗炎 C反应蛋白 丙二醛 |
| 收稿时间： | 12 16 2005 12:00AM |
| 修稿时间： | 2005年12月16 |
Anti-inflammatory effects of red yeast rice |
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| WANG Yan-yan,ZHAO Zheng,HUANG Feng,REN Jian-ping.Anti-inflammatory effects of red yeast rice[J].Chinese Remedies & Clinics,2006,6(5):350-352. |
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| Authors: | WANG Yan-yan ZHAO Zheng HUANG Feng REN Jian-ping |
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| Affiliation: | Department of Rheumatology, Chinese PLA General Hospital, Beijing 100853,China |
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| Abstract: | Objective To study the mechanism of anti-inflammatory action of red yeast rice. Methods Red air-pouch acute inflammatory model was used by subcutaneous injection of carrageenan,then determine the content of efflusion,white blood cell(WBC) count, C-reaction protein(CRP),molondialdehyde(MDA)content of efflusion and CRP,MDA content of blood serum. Results Red yeast rice could reduce the content of efflusion,decrease WBC count,CRP,MDA content of efflusion and CRP,MDA content of blood serum. Conclusion The mechanism of anti-inflammatory action of red yeast rice are related to the reduction of inflammatory agent, CRP and MDA contents. |
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| Keywords: | Monascus Anti-inflammaory C-reaction protein Malondialdehyde |
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