曲马多联合甲氧氯普胺治疗剖宫产术中寒颤的临床观察

目的观察曲马多联合甲氧氯普胺对剖宫产术中寒颤的治疗效果及不良反应。方法拟择期行剖宫产术产妇100例,ASA1-2级,随机分为二组:曲马多组(T组),曲马多联合甲氧氯普胺组(MT组)。胎儿取出后T组给予曲马多1mg/kg静注,MT组给予甲氧氯普胺10mg静注之后再给予曲马多1mg/kg静注。观察寒颤评分、恶心呕吐、头晕、呼吸抑制及锥体外系反应发生情况。结果曲马多组寒颤缓解率为97%,治愈率为82%,恶心呕吐发生率为70%,曲马多联合甲氧氯普胺组恶心呕吐发生率降低86%。结论曲马多1mg/kg能有效预防和治疗剖宫产术中的寒颤,甲氧氯普胺能有效减少曲马多引起的恶心呕吐。

Clinical Observation of Tramadol and Metoclopramide in Treatment of Shivering During Cesarean Section

Objective To observe treatment effect and adverse reactions of using tramadol and metoclopramide to treat shivering in cesarean section. Methods One hundred ASA I-II parturient patients, who were undergoing elective cesarean section, were included in the study. They were randomly assigned to one of two groups - Group T and Group MT. Group T receives lrng/kg tramadol iv after delivery. Group MT receives 10mg metoclopramide iv followed by lmg/kg tramadol iv. Monitor scale of shivering, incidence of nausea and vomiting, dizziness, respiratory depression and incidence of extrapyramidal reactions. Results 97% remission rate and 82% cure rate of shivering was observed after tramadol was given. Group T showed 70% incidence of nausea and vomiting. Group MT showed 86% less incidence of nausea and vomiting compared to Group T. Conclusion lmg/kg tramadol is effective in preventing and treating shivering in cesarean section. Metoclopramide is effective in reducing nausea and vomiting caused by tramadol.