| 吉西他滨联合长春瑞宾或顺铂治疗晚期非小细胞肺癌临床观察 |
| |
| 引用本文： | 张琼,郭其森,董宁宁. 吉西他滨联合长春瑞宾或顺铂治疗晚期非小细胞肺癌临床观察[J]. 山东医药, 2008, 48(39): 19-20 |
| |
| 作者姓名： | 张琼 郭其森 董宁宁 |
| |
| 作者单位： | 山东省肿瘤医院,山东济南,250117;山东省肿瘤医院,山东济南,250117;山东省肿瘤医院,山东济南,250117 |
| |
| 摘 要： | 目的观察吉西他滨联合长春瑞宾或顺铂治疗晚期非小细胞肺癌的临床疗效和不良反应。方法50例非小细胞肺癌患者随机分为GN组25例、GP组25例;GN组给予吉西他滨联合长春瑞宾进行化疗,GP组给予吉西他滨联合顺铂进行化疗,共2-3个周期。结果GN组有效率36%、中位生存期9.9个月、1 a生存率44.7%,GP组分别为40%、10.1个月、40%,两组相比,P均〉0.05;GN、GP组恶心、呕吐发生率分别为40%和76%,两组相比,P〈0.05。结论吉西他滨联合长春瑞宾或顺铂治疗晚期非小细胞肺癌疗效相近,吉西他滨联合长春瑞宾不良反应较小,患者更易耐受。
|
| 关 键 词： | 肺肿瘤 非小细胞肺癌 吉西他滨 长春瑞宾 顺铂 |
Clinical observation of gemcitabine combined with vinorelbine or cisplatin in the treatment of advanced non-small cell lung cancer |
| |
| ZHANG Qiong,GUO Qi-sen,DONG Ning-ning. Clinical observation of gemcitabine combined with vinorelbine or cisplatin in the treatment of advanced non-small cell lung cancer[J]. Shandong Medical Journal, 2008, 48(39): 19-20 |
| |
| Authors: | ZHANG Qiong GUO Qi-sen DONG Ning-ning |
| |
| Affiliation: | Shandong Tumor Hospital;Jinan 250117;P.R.China |
| |
| Abstract: | Objective To observe the efficacy and toxicity of vinorelbine or cisplatin combined with gemcitabine for patients with non-small cell lung cancer(NSCLC).Methods 50 NSCLC patients were divided into 2 groups,25 cases in vinorelbine group and 25 cases in cisplatin group.Results The overall response rate was 36% in the vinorelbine group and 40% in the cisplatin group.The median survival time was 9.9 months in the vinorelbine group and 10.1 months in the cispaltin group.There was no statistically significant dif... |
| |
| Keywords: | lung neoplasmas non-small cell lung cancer gemcitabine vinorelbine cisplatin |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
