Can high-dose immunoglobulin therapy be indicated in neonatal rhesus haemolysis? |
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| Authors: | S. Kubo T. Ariga H. Tsuneta T. Ishii |
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| Affiliation: | (1) Department of Paediatrics, Hokkaido Central Hospital for Social Health Insurance, 1-8 Nakanoshima, Toyohira-Ku, 062 Sapporo, Japan |
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| Abstract: | A male neonate with hyperbilirubinaemia and progressing anaemia due to rhesus (c+E) incompatibility received high dose intravenous gammaglobulin (ivIgG) therapy at 13 days of age. Clinical response to therapy was confirmed by a rapid decrease in serum bilirubin level, and with the prevention of a further decline of the haemoglobin level. No side-effects were noted. High dose ivIgG therapy could be an alternative to (exchange) blood transfusion in case of some haemolytic diseases of newborn. |
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| Keywords: | High dose intravenous gammaglobulin therapy Haemolytic disease of newborn Rhesus incompatibility |
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