不同出生体质量、性别新生儿脐血黄体生成素、卵泡刺激素、睾酮的水平变化

目的探讨脐血黄体生成素（LH）．卵泡刺激素（FSH）和睾酮（T）在不同出生体质量、性别新生儿脐血中的差异及其对胎儿生长发育的影响。方法根据新生儿出生体质量分为3组，其中巨大儿组28例，官内发育迟缓儿（IUGR）组31例；正常新生儿组71例。采用放射免疫分析法检测3组新生儿脐血LH,FSH和T水平。结果1．男性新生儿脐血LH、FSH和T水平均显著高于女性者（P〈0．001，0．05）；2．IUGR组脐血LH水平显著高于正常新生儿组（P〈0．05），而FSH水平显著低于正常组（P〈0．01）。结论脐血LH、FSH和T水平与胎儿性别有相关性，脐血LH与IUGR的发生有关。

Changes of Luteinizing Hormone, Follicle-Stimulating Hormone and Testosterone in Umbilical Vein Blood of Neonates with Different Birth Weight and Sexes

Objective To observe changes of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and testosterone (T) in umbilical vein blood between male and female neonates, and assess the effect of serum LH, FSH and T on fetal growth.Methods Umbilical vein blood was obtained from 130 neonates (64 females and 66 males) in the second hospital of changshu city. According to birth weight, 130 neonates were divided into 3 groups: macrosomia (n=28), intrauterine growth restriction (IUGR) (n=31) and normal neonates (n=71). The serum levels of LH, FSH and T were measured by radioimmunoassay.Results 1.The levels of LH, FSH and T in umbilical vein blood were significantly higher in male neonates than those in females (P<0.001,0.05,0.05);2. LH level in umbilical vein blood was significantly higher in IUGR neonates than that in normal neonates,FSH level was significantly lower in IUGR neonates than that in normal neonates(P<0.01) .Conclusion The levels of LH, FSH and T are associated with fetal sex, and LH has a relationship with IUGR.