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幽门螺杆菌感染以及根治后对肝硬化患者血氨浓度的影响
引用本文:姜敏,张义侠,郑有贵,傅宝玉.幽门螺杆菌感染以及根治后对肝硬化患者血氨浓度的影响[J].中国医科大学学报,2004,33(2):178-179.
作者姓名:姜敏  张义侠  郑有贵  傅宝玉
作者单位:中国医科大学附属第一医院消化内科,辽宁,沈阳,110001
摘    要:目的:探讨幽门螺杆菌感染及根治后对肝硬化患者血氨浓度的影响.方法:用13C-呼气实验方法,选择50例肝硬化门脉高压患者作为实验组,对其中36例幽门螺杆菌阳性者,检测根治幽门螺杆菌前后血氨浓度的变化,27例胃病患者为对照组.结果:肝硬化门脉高压合并幽门螺杆菌感染组,血氨明显升高(P<0.01),根治后血氨降低(P<0.01).结论:幽门螺杆菌感染可导致肝硬化门脉高压患者血氨升高,根治后能降低血氨浓度.

关 键 词:肝硬化门脉高压  幽门螺杆菌  血氨
文章编号:0258-4646(2004)02-0178-02
修稿时间:2003年1月6日

Effects of helicobacter pylori infection and eradication therapy on hyperammonaemia in patients with liver cirrhosis
JIANG Min,ZHANG Yi-xia,ZHENG You-gui,FU Bao-yu.Effects of helicobacter pylori infection and eradication therapy on hyperammonaemia in patients with liver cirrhosis[J].Journal of China Medical University,2004,33(2):178-179.
Authors:JIANG Min  ZHANG Yi-xia  ZHENG You-gui  FU Bao-yu
Abstract:Objective: To study effects of helicobacter pylori infection and eradication therapy on hyperammonaemia in patients with liver cirrhosis. Methods: Ammonia concentrations in blood and 13 C-urea breath text were examined. The blood ammonia concentration and 13 C-urea breath text were analysed again after eradication in the patients with helicobacter pylori-positive liver cirrhosis. Results: The blood ammonia concentration in patients with helicobacter pylori-positive liver cirrhosis was significantly higher than that of patients with helicobacter pylori-negative liver cirrhosis and gastric diseases(P<0.01). The blood ammonia concentration after eradication was significantly lower than that before eradication in the patients with helicobacter pylori-positive liver cirrhosis. Conclusion: Helicobacter pylori infection could induce hyperammonaemia in patients with liver cirrhosis and the eradication of helicobacter pylori is effective in the patients with hyperammonaemia.
Keywords:helicobacter pylori  liver cirrhosis  hyperammonaemia
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