脑梗死超早期动脉溶栓后证候演变观察

目的探讨急性脑梗死超早期动脉溶栓后中医证候的演变。方法采用前瞻、对照方法,分析40例超早期脑梗死动脉溶栓后中医证候的动态演变。结果治疗14 d后,34例风证全部消失,气虚证由治疗前的0例变为8例,火证由治疗前的22例变为9例。瘀证在治疗前后的出现频率均为100%。急性脑梗死在超早期以实证为主,随着病程的发展,风证逐渐消失,实证的比例下降。而虚证,特别是气虚证的比例开始增加,瘀证在整个过程中则一直存在。治疗组证候的变化与保守治疗组没有明显差别。结论溶栓治疗对脑梗死超早期的证候演变没有产生明显的影响,治疗组的证候变化符合急性脑梗死超早期的总体证候演变规律。

Evolution of TCM Syndromes in Super Early Acute Cerebral Infarction after Thrombolytic Therapy

Objective To study the evolution of traditional Chinese medicine（TCM）syndromes in super early acute cerebral infarction after arterial thrombolysis.Methods The evolution of TCM syndromes in super early acute cerebral infarction after arterial thrombolysis was studied in 40 patients（pts）.Results At 14 days after treatment,the wind syndrome disappeared in all 34 pts.Qi-deficiency syndrome showed a obvious upward trend to 8 cases.The fire syndrome showed a downward trend from 22 cases to 9 casess.Blood stasis syndrome was in all pts pre-and post-emergence.The main syndrome was sthenia related syndrome in super early acute cerebral infarction.Gradually,the sthenia related syndromes showed a downward trend while the asthenia related syndromes showed a obvious upward trend.Conclusion The thrombolytic therapy had no significant impact on the evolution of TCM syndromes in super early acute cerebral infarction.