复方调脂降糖汤治疗糖尿病代谢综合征的临床观察 |
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引用本文: | 刘春华,颜旭,庄红,陈琪,赵启. 复方调脂降糖汤治疗糖尿病代谢综合征的临床观察[J]. 中医药研究, 2011, 0(1): 10-12 |
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作者姓名: | 刘春华 颜旭 庄红 陈琪 赵启 |
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作者单位: | 湖南省中医药研究院附属医院,410006 |
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摘 要: | 目的观察复方调脂降糖汤治疗2型糖尿病(T2DM)代谢综合征(MS)的临床疗效。方法将符合入选标准的134例以2型糖尿病代谢综合征患者分为治疗组(67例)和对照组(67例)。对照组常规给予降糖、降压药物,使血糖、血压达到稳定且符合入组条件,治疗组在对照组用药基础上给予复方调脂降糖汤口服。检测两组治疗前及治疗4周、8周后空腹血糖、血脂、血清胰岛素、糖化血红蛋白、腰围和减轻体重等指标。结果两组治疗8周后,在三酰甘油、高密度脂蛋白、体重、空腹血糖、空腹胰岛素、胰岛素抵抗指数、腰围等指标较治疗前有明显改善(P〈0.05),其中治疗组低密度脂蛋白、体重、空腹胰岛素、胰岛素抵抗指数等指标优于对照组(P〈0.05)。结论复方调脂降糖汤具有明显改善胰岛素抵抗作用,同时可以降糖、调脂、减小腰围和体重,缓解MS的多种危害因素。
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关 键 词: | 复方调脂降糖汤 2型糖尿病 代谢综合征 |
Compound Tiaozhi Jiangtang Decoction in Treatment of Metabolic Syndrome with Type 2 Diabetes Mellitus |
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Affiliation: | Liu Chunhua,Yan Xu,Chen Qi,et al Department of Endocrine,Affiliated Hospital,Hunan Academe of Traditional Chinese Medicine(Hunan 410006) |
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Abstract: | Objective To observe the effects of compound Tiaozhi Jiangtang decoction(Co-TZJT) on metabolic syndrome(MS) and type 2 diabetes mellitus(T2DM).Methods One hundred and thirty-four patients(pts) with MS and T2DM were randomly assigned to two groups:Control group(n=67) treated with routine therapy and treatment group(n=67) treated with Co-TZJT and routine therapy.Fasting blood glucose(FBG),blood lipid(BL),insulin,glycosylated hemoglobin(HbA1C),weight and waist circumference were checked at the end of 4th and 8th week.Results The FBG,blood lipid,insulin,and HbA1C were improved in Co-TZTT group.Conclusion Co-TZJT could improve insulin resistance and reduce harmful factors of MS. |
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Keywords: | compound Tiaozhi Jiangtang decoction type 2 diabetes mellitus metabolic syndrome |
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