氯丙咪嗪与舒必利辅助治疗精神分裂症阴性症状的对照研究 |
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引用本文: | 朱玉卿!,张素娟!,张德兵!.氯丙咪嗪与舒必利辅助治疗精神分裂症阴性症状的对照研究[J].临床精神医学杂志,1999(4). |
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作者姓名: | 朱玉卿! 张素娟! 张德兵! |
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作者单位: | 安徽宿县地区第二人民医院 |
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摘 要: | 目的: 比较氯丙咪嗪、舒必利辅助治疗精神分裂症阴性症状的效果。 方法: 使用氯丙咪嗪、舒必利分别作为氯氮平的辅助用药与单用氯氮平对88 例以阴性症状为主的精神分裂症病人进行对照研究; 以简明精神病评定量表、阴性症状量表和副反应量表进行评定。 结果: 合并氯丙咪嗪组、舒必利组及单用氯氮平组对阴性症状的治疗显效率分别为69% 、31% 、1333% 。 结论: 氯氮平合并氯丙咪嗪治疗能有效地改善精神分裂症的阴性症状。
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关 键 词: | 精神分裂症 阴性症状 氯丙咪嗪 舒必利 |
A controlled trial comparing chlorimipramine and sulpiride as adjunct to clozapine in the treatment of negative symptoms of schizophrenia |
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Abstract: | Objective:To compare chlorimipramine and sulpiride as adjunct in the treatment of negative symptoms in schizophrenic patients. Method:88 inpatients with diagnosis of chronic schizophrenia with negative symptoms were treated clozapine alone,clozapine/chlorimipramine combined,or clozapine/sulpiride combined regime.Clinical progress was monitored with BPRS,SANS and TESS. Results:The response rate for negative symptoms in the clozapine/chlorimipramine combined, clozapine/sulpiride combined and clozapine alone group were 69%,31%,and 13 3% respectively. Conclusion:Negative symptoms of schizophrenia could be improved effectively with clozapine combined with chlorimipramine. |
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Keywords: | Schizophrenia Negative symptoms Chlorimipramine Sulpiride |
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