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早期糖尿病肾病患者血清中同型半胱氨酸和胱抑素C水平变化及其意义
引用本文:邰文静,芮星,杨义伟,唐国建.早期糖尿病肾病患者血清中同型半胱氨酸和胱抑素C水平变化及其意义[J].医药论坛杂志,2011(19):46-47,50.
作者姓名:邰文静  芮星  杨义伟  唐国建
作者单位:金坛市人民医院检验科;
摘    要:目的探讨早期糖尿病肾病患者血清中同型半胱氨酸(Hcy)和胱抑素C(CysC)水平的变化及其意义。方法分别应用酶法和免疫比浊法检测100例早期糖尿病肾病患者和100例健康对照者血清中Hcy和CysC水平的变化。结果早期糖尿病肾病组血清中同型半胱氨酸和胱抑素C水平显著高于对照组,差异有统计学意义(P<0.05)。结论血清中Hcy和Cys-C水平变化可作为早期糖尿病肾病患者早期肾损伤一个理想的指标,两者联合检测对早期糖尿病肾病诊断具有重要意义。

关 键 词:糖尿病肾病  同型半胱氨酸  胱抑素C

Changes and significance of serum homocysteine and cystatin C in early diabetic nephropathy
TAI Wen-jing,RUI Xing,YANG Yi-wei,TANG Guo-jian.Changes and significance of serum homocysteine and cystatin C in early diabetic nephropathy[J].Journal of Medical Forum,2011(19):46-47,50.
Authors:TAI Wen-jing  RUI Xing  YANG Yi-wei  TANG Guo-jian
Institution:TAI Wen-jing,RUI Xing,YANG Yi-wei,TANG Guo-jian Department of Clinical Laboratory,the People's Hospital of Jintan,Jintan,Jiangsu 213200,China
Abstract:Objective To study the changes and significance of serum homocysteine and cystatin C in early diabetic nephropathy.Methods The levels of HCY and Cystatin C in the samples included 100 patients with early diabetic nephropathy and 100 healthy controls was studied by immunoturbidimetric assay and enzymatic method.Results The levels of serum homocysteine and Cystatin C elevated more significantly in patients with EDN than those of the healthy controls(P<0.05).Conclusions The levels of serum homocysteine and Cys...
Keywords:Diabetic nephropathy  HCY  Cystatin C  
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