光凝虹膜联合小梁切除及应用丝裂霉素治疗新生血管性青光眼

目的评价氩绿激光行虹膜及前房角新生血管光凝联合小梁切除术,术中应用丝裂霉素C(MMC)治疗新生血管性青光眼的疗效。方法对28例(28眼)新生血管性青光眼先用氩激光对虹膜及前房角小梁网新生血管进行直接覆盖光凝,观察新生血管闭塞萎缩后,行小梁切除术联合术中应用0.2mg/ml MMC,术后观察降眼压效果、结膜滤过泡情况、眼前节炎症反应及其它手术并发症;随访时间为6～24个月。结果 28例术后第1周平均眼压(10.52±3.16)mm Hg较术前平均眼压(48.36±5.87)mm Hg明显降低(t=14.86,P=0.000),随访时眼压控制良好,平均(17.48±3.23)mm Hg,仅3例需用药物控制,术后眼压较治疗前有显著意义的降低(P<0.01)。23例结膜滤过泡弥散隆起,4例较为扁平,1例结膜切口II期愈合;6个月后功能性滤过泡存在有21例(21/28)。术中6例少量前房出血,术后2例继发少量前房出血。新生血管在术后早期全部消退,3月后出现3例(3/28);余无其它严重并发症发生。结论氩激光联合小梁切除术加术中应用丝裂霉素C是治疗新生血管性青光眼的一种有效方法。

Laser treatment of iris neovascularization combined with trabeculectomy and MMC for neovascular glaucoma

Objective To evaluate the effectiveness of laser coagulation of iris neovascularization combined with trabeculectomy and used MMC in the operation for neovascular glaucoma.Methods In 28 cases(16male,12female) of neovascular glaucoma,the green argon laser therapy to iris and Trabecular meshwork neovascularization was first conducted followed by routine trabeculectomy.Mitomycin C was applied in all cases.The change of intraocular pressure(IOP),filtering bleb as well as the reaction in the anterior segment of ...