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栀子对胃肠平滑肌条运动的影响
引用本文:杨淑娟,焦效兰,马青,汤治元.栀子对胃肠平滑肌条运动的影响[J].浙江医学,2008,30(9).
作者姓名:杨淑娟  焦效兰  马青  汤治元
作者单位:宁波大学医学院生理室,315211
摘    要:目的 观察利胆药物-栀子对兔离体小肠平滑肌的影响,并初步探讨其作用机制.方法 取兔十二指肠纵行肌条,安置在各恒温灌流肌槽中并用BL-310生物技能实验系统记录十二指肠平滑肌条的收缩活动.结果 栀子显著升高兔十二指肠肌条张力及收缩频率.减小其收缩波平均振幅,并有剂量依赖关系.结论 栀子对十二指肠肌条收缩活动具有明显的兴奋作用,这种兴奋作用部分经由M受体介导.

关 键 词:十二指肠平滑肌条  栀子  收缩活动  阿托品

Effect of Gardenia on contractile activity of isolated duodenum muscle strips in rabbits
YANG Shujuan,JIAO Xiaolan,MA Qing,et al..Effect of Gardenia on contractile activity of isolated duodenum muscle strips in rabbits[J].Zhejiang Medical Journal,2008,30(9).
Authors:YANG Shujuan  JIAO Xiaolan  MA Qing  
Institution:YANG Shujuan,JIAO Xiaolan,MA Qing,et al. Department of Physiology,Medical College of Ningbo University,Ningbo 315211,China
Abstract:Objective To investigate the effects of Gardenia (Zhizi) on contractile activity of isolated duodenum muscle strips in rabbits and its mechanism. Methods Longitudinal muscle strips of duodenum were taken from rabbits. Each isolated muscle strips were put in a tissue chamber containing 5ml Krebs solution and the motility of muscle strips was recorded simultaneously. Results Gardenia increased the resting tension and contractile frequency of longitudinal muscle strips of duodenum, and decreased mean contracti...
Keywords:Longitudinal muscle strips of duodenum Zhizi Muscle contraction Atropine  
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