Transient acantholytic dermatosis associated with lymphomatous angioimmunoblastic lymphadenopathy |
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| Authors: | B D Zelickson A Tefferi M A Gertz P M Banks M R Pittelkow |
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| Affiliation: | Department of Dermatology, Mayo Clinic Rochester, Minnesota 55905. |
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| Abstract: | Transient acantholytic dermatosis is a papulovesicular cutaneous eruption first described in 1970. There have been subsequent reports of similar disorders occurring in patients with malignancy. Angioimmunoblastic lymphadenopathy with dysproteinemia is a disorder characterized by an acute onset of generalized lymphadenopathy associated with fever, malaise, pruritus, night sweats, and hepatosplenomegaly. The patient described had a papular acantholytic dermatosis associated with the development of angioimmunoblastic lymphadenopathy with dysproteinemia-like T-cell lymphoma. The cutaneous manifestations of angioimmunoblastic lymphadenopathy with dysproteinemia are discussed. |
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